SGIP1 information

SGIP1
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	5AWR, 5AWT, 5AWU, 5AWS
Identifiers
Aliases	SGIP1, SH3 domain GRB2 like endophilin interacting protein 1, SH3GL interacting endocytic adaptor 1
External IDs	OMIM: 611540 MGI: 1920344 HomoloGene: 13001 GeneCards: SGIP1
Gene location (Human)
Chr.	Chromosome 1 (human)
End	66,751,139 bp
Gene location (Mouse)
Chr.	Chromosome 4 (mouse)
End	102,973,628 bp
RNA expression pattern
	Top expressed in
	stromal cell of endometrium; ; ascending aorta; ; prefrontal cortex; ; middle temporal gyrus; ; Brodmann area 46; ; Brodmann area 23; ; endothelial cell; ; nucleus accumbens; ; dorsolateral prefrontal cortex; ; cingulate gyrus;
	Top expressed in
	superior frontal gyrus; ; substantia nigra; ; piriform cortex; ; medial dorsal nucleus; ; cerebellar cortex; ; medial geniculate nucleus; ; olfactory tubercle; ; primary motor cortex; ; lateral geniculate nucleus; ; hippocampus proper;
	More reference expression data
	n/a
Gene ontology
Molecular function	microtubule binding; SH3 domain binding; tubulin binding; protein binding; phospholipid binding; cytoskeletal protein binding;
Cellular component	cytoplasm; plasma membrane; clathrin-coated pit; AP-2 adaptor complex; membrane; clathrin-coated vesicle; cytosol; cytoskeleton;
Biological process	positive regulation of receptor-mediated endocytosis; endocytosis; plasma membrane tubulation; membrane organization; response to dietary excess; positive regulation of feeding behavior; clathrin-dependent endocytosis; energy homeostasis; clathrin coat assembly;
	Sources:Amigo / QuickGO
Orthologs
	84251
	73094
	ENSG00000118473
	ENSMUSG00000028524
	Q9BQI5
	Q8VD37
NM_001308203; NM_032291; NM_001350217; NM_001350218; NM_001376534;
	NM_001376535; NM_001376536; NM_001376537; NM_001376538; NM_001376539; NM_001376540; NM_001376541; NM_001376542; NM_001376543; NM_001376544; NM_001376545; NM_001376546; NM_001376547; NM_001376548; NM_001376549; NM_001376550; NM_001376551; NM_001376552; NM_001376554; NM_001376555; NM_001376556; NM_001376557
	NM_001285852; NM_001285859; NM_001285860; NM_001285862; NM_144906
NP_001295132; NP_115667; NP_001337146; NP_001337147; NP_001363463;
	NP_001363464; NP_001363465; NP_001363466; NP_001363467; NP_001363468; NP_001363469; NP_001363470; NP_001363471; NP_001363472; NP_001363473; NP_001363474; NP_001363475; NP_001363476; NP_001363477; NP_001363478; NP_001363479; NP_001363480; NP_001363481; NP_001363483; NP_001363484; NP_001363485; NP_001363486
	NP_001272781; NP_001272788; NP_001272789; NP_001272791; NP_659155
	Wikidata
View/Edit Human	View/Edit Mouse

SH3-containing GRB2-like protein 3-interacting protein 1 is a protein that in humans is encoded by the SGIP1 gene.^[5]^[6]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000118473 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000028524 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Wiemann S, Weil B, Wellenreuther R, Gassenhuber J, Glassl S, Ansorge W, Bocher M, Blocker H, Bauersachs S, Blum H, Lauber J, Dusterhoft A, Beyer A, Kohrer K, Strack N, Mewes HW, Ottenwalder B, Obermaier B, Tampe J, Heubner D, Wambutt R, Korn B, Klein M, Poustka A (Mar 2001). "Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs". Genome Res. 11 (3): 422–35. doi:10.1101/gr.GR1547R. PMC 311072. PMID 11230166.
^ "Entrez Gene: SGIP1 SH3-domain GRB2-like (endophilin) interacting protein 1".

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000118473 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000028524 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid11230166-5] Wiemann S, Weil B, Wellenreuther R, Gassenhuber J, Glassl S, Ansorge W, Bocher M, Blocker H, Bauersachs S, Blum H, Lauber J, Dusterhoft A, Beyer A, Kohrer K, Strack N, Mewes HW, Ottenwalder B, Obermaier B, Tampe J, Heubner D, Wambutt R, Korn B, Klein M, Poustka A (Mar 2001). "Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs". Genome Res. 11 (3): 422–35. doi:10.1101/gr.GR1547R. PMC 311072. PMID 11230166.

[entrez-6] "Entrez Gene: SGIP1 SH3-domain GRB2-like (endophilin) interacting protein 1".

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Active zone