SEC22B information

SEC22B
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	2NUP, 2NUT, 3EGD, 3EGX
Identifiers
Aliases	SEC22B, ERS-24, SEC22L1, SEC22 homolog B, vesicle trafficking protein (gene/pseudogene), SEC22 homolog B, vesicle trafficking protein
External IDs	OMIM: 604029; MGI: 1338759; HomoloGene: 3597; GeneCards: SEC22B; OMA:SEC22B - orthologs
Gene location (Human)
Chr.	Chromosome 1 (human)
End	120,176,520 bp
Gene location (Mouse)
Chr.	Chromosome 3 (mouse)
End	97,830,592 bp
RNA expression pattern
	Top expressed in
	Achilles tendon; ; body of pancreas; ; islet of Langerhans; ; stromal cell of endometrium; ; anterior pituitary; ; epithelium of colon; ; rectum; ; monocyte; ; left adrenal gland; ; Descending thoracic aorta;
	Top expressed in
	cumulus cell; ; endocardial cushion; ; neural layer of retina; ; yolk sac; ; molar; ; lacrimal gland; ; islet of Langerhans; ; calvaria; ; primitive streak; ; seminal vesicula;
	More reference expression data
	n/a
Gene ontology
Molecular function	SNAP receptor activity; protein binding; syntaxin binding; SNARE binding;
Cellular component	integral component of membrane; Golgi apparatus; endoplasmic reticulum membrane; membrane; melanosome; endoplasmic reticulum; endoplasmic reticulum-Golgi intermediate compartment membrane; endoplasmic reticulum-Golgi intermediate compartment; SNARE complex; Golgi membrane; transport vesicle; phagocytic vesicle membrane; ER to Golgi transport vesicle membrane; synaptic vesicle;
Biological process	positive regulation of protein catabolic process; vesicle fusion with Golgi apparatus; COPII vesicle coating; protein transport; vesicle-mediated transport; exocytosis; retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; endoplasmic reticulum to Golgi vesicle-mediated transport; vesicle fusion with endoplasmic reticulum-Golgi intermediate compartment (ERGIC) membrane; negative regulation of autophagosome assembly;
	Sources:Amigo / QuickGO
Orthologs
	9554
	20333
	ENSG00000265808
	ENSMUSG00000027879
	O75396
	O08547
	NM_004892
	NM_011342
	NP_004883
	NP_035472
	Wikidata
View/Edit Human	View/Edit Mouse

Vesicle-trafficking protein SEC22b is a protein that in humans is encoded by the SEC22B gene.^[5]^[6]^[7]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000265808 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000027879 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Hay JC, Chao DS, Kuo CS, Scheller RH (April 1997). "Protein interactions regulating vesicle transport between the endoplasmic reticulum and Golgi apparatus in mammalian cells". Cell. 89 (1): 149–58. doi:10.1016/S0092-8674(00)80191-9. PMID 9094723. S2CID 8682509.
^ Okumura AJ, Hatsuzawa K, Tamura T, Nagaya H, Saeki K, Okumura F, Nagao K, Nishikawa M, Yoshimura A, Wada I (February 2006). "Involvement of a novel Q-SNARE, D12, in quality control of the endomembrane system". The Journal of Biological Chemistry. 281 (7): 4495–506. doi:10.1074/jbc.M509715200. PMID 16354670.
^ "Entrez Gene: SEC22B SEC22 vesicle trafficking protein homolog B (S. cerevisiae)".

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000265808 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000027879 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid9094723-5] Hay JC, Chao DS, Kuo CS, Scheller RH (April 1997). "Protein interactions regulating vesicle transport between the endoplasmic reticulum and Golgi apparatus in mammalian cells". Cell. 89 (1): 149–58. doi:10.1016/S0092-8674(00)80191-9. PMID 9094723. S2CID 8682509.

[pmid16354670-6] Okumura AJ, Hatsuzawa K, Tamura T, Nagaya H, Saeki K, Okumura F, Nagao K, Nishikawa M, Yoshimura A, Wada I (February 2006). "Involvement of a novel Q-SNARE, D12, in quality control of the endomembrane system". The Journal of Biological Chemistry. 281 (7): 4495–506. doi:10.1074/jbc.M509715200. PMID 16354670.

[entrez-7] "Entrez Gene: SEC22B SEC22 vesicle trafficking protein homolog B (S. cerevisiae)".

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