SCP2 information

SCP2
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	1QND, 2C0L
Identifiers
Aliases	SCP2, NLTP, NSL-TP, SCP-2, SCP-CHI, SCP-X, SCPX, sterol carrier protein 2, SCOX
External IDs	OMIM: 184755; MGI: 98254; HomoloGene: 37717; GeneCards: SCP2; OMA:SCP2 - orthologs
Gene location (Human)
Chr.	Chromosome 1 (human)
End	53,051,698 bp
Gene location (Mouse)
Chr.	Chromosome 4 (mouse)
End	108,002,195 bp
RNA expression pattern
	Top expressed in
	jejunal mucosa; ; right lobe of liver; ; palpebral conjunctiva; ; germinal epithelium; ; duodenum; ; rectum; ; gallbladder; ; pylorus; ; islet of Langerhans; ; oral cavity;
	Top expressed in
	proximal tubule; ; white adipose tissue; ; hepatobiliary system; ; liver; ; jejunum; ; duodenum; ; kidney; ; colon; ; ileum; ; lens;
	More reference expression data
	n/a
Gene ontology
Molecular function	transferase activity; phosphatidylinositol transfer activity; fatty-acyl-CoA binding; acyltransferase activity, transferring groups other than amino-acyl groups; sterol transporter activity; oleic acid binding; long-chain fatty acyl-CoA binding; cholesterol binding; protein binding; propanoyl-CoA C-acyltransferase activity; catalytic activity; signaling receptor binding; acyltransferase activity; lipid binding; propionyl-CoA C2-trimethyltridecanoyltransferase activity;
Cellular component	membrane; intracellular membrane-bounded organelle; peroxisome; nucleoplasm; peroxisomal matrix; mitochondrion; extracellular exosome; cytoplasm; cytosol; protein-containing complex;
Biological process	progesterone biosynthetic process; peroxisome organization; lipid transport; inositol trisphosphate biosynthetic process; alpha-linolenic acid metabolic process; positive regulation of steroid metabolic process; lipid hydroperoxide transport; positive regulation of intracellular cholesterol transport; fatty acid beta-oxidation using acyl-CoA oxidase; metabolism; protein localization to plasma membrane; bile acid biosynthetic process; sterol transport; steroid biosynthetic process; phospholipid transport; transport; protein targeting to peroxisome;
	Sources:Amigo / QuickGO
Orthologs
	6342
	20280
	ENSG00000116171
	ENSMUSG00000028603
	P22307
	P32020
NM_001007098; NM_001007099; NM_001007100; NM_001007250; NM_001193599;
	NM_001193600; NM_001193617; NM_002979; NM_001330587
	NM_011327
NP_001007099; NP_001007100; NP_001007101; NP_001007251; NP_001180528;
	NP_001180529; NP_001180546; NP_001317516; NP_002970
	NP_035457
	Wikidata
View/Edit Human	View/Edit Mouse

Non-specific lipid-transfer protein also known as sterol carrier protein 2 (SCP-2) or propanoyl-CoA C-acyltransferase is a protein that in humans is encoded by the SCP2 gene.^[5]^[6]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000116171 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000028603 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Yamamoto R, Kallen CB, Babalola GO, Rennert H, Billheimer JT, Strauss JF (January 1991). "Cloning and expression of a cDNA encoding human sterol carrier protein 2". Proc. Natl. Acad. Sci. U.S.A. 88 (2): 463–7. Bibcode:1991PNAS...88..463Y. doi:10.1073/pnas.88.2.463. PMC 50831. PMID 1703300.
^ He Z, Yamamoto R, Furth EE, Schantz LJ, Naylor SL, George H, Billheimer JT, Strauss JF (October 1991). "cDNAs encoding members of a family of proteins related to human sterol carrier protein 2 and assignment of the gene to human chromosome 1 p21----pter". DNA Cell Biol. 10 (8): 559–69. doi:10.1089/dna.1991.10.559. PMID 1718316.

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000116171 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000028603 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid1703300-5] Yamamoto R, Kallen CB, Babalola GO, Rennert H, Billheimer JT, Strauss JF (January 1991). "Cloning and expression of a cDNA encoding human sterol carrier protein 2". Proc. Natl. Acad. Sci. U.S.A. 88 (2): 463–7. Bibcode:1991PNAS...88..463Y. doi:10.1073/pnas.88.2.463. PMC 50831. PMID 1703300.

[pmid1718316-6] He Z, Yamamoto R, Furth EE, Schantz LJ, Naylor SL, George H, Billheimer JT, Strauss JF (October 1991). "cDNAs encoding members of a family of proteins related to human sterol carrier protein 2 and assignment of the gene to human chromosome 1 p21----pter". DNA Cell Biol. 10 (8): 559–69. doi:10.1089/dna.1991.10.559. PMID 1718316.

SCP2 information

and 9 Related for: SCP2 information

SCP2

WS FTP

Thiolase

Steroidogenic acute regulatory protein

Juvenile hormone diol kinase

CTDSP2

Caveolin 1

Sterol carrier protein

SMC1B