Substance for topical application that produces redness of the skin
A rubefacient is a substance for topical application that produces redness of the skin, e.g. by causing dilation of the capillaries and an increase in blood circulation. It has sometimes been used to relieve acute or chronic pain, but there is limited evidence as to its efficacy,[1][2] and as of 2014 the best evidence does not support using gels and creams containing rubefacients for this purpose.[1][better source needed]
^ abDerry, S; Matthews, P; Wiffen, PJ; Moore, RA (2014). "Salicylate-containing rubefacients for acute and chronic musculoskeletal pain in adults". Cochrane Database of Systematic Reviews. 2014 (3): CD007403. doi:10.1002/14651858.CD007403.pub3. PMC 6458007. PMID 25425092.
^Mason et al. 2004 Systematic review of efficacy of topical rubefacients containing salicylates for the treatment of acute and chronic pain BMJ 328:995
A rubefacient is a substance for topical application that produces redness of the skin, e.g. by causing dilation of the capillaries and an increase in...
Ranunculus species in traditional medicines are as an antirheumatic, as a rubefacient, and to treat intermittent fever. The findings in some Ranunculus species...
wintergreen). Methyl salicylate is used in high concentrations as a rubefacient and analgesic in deep heating liniments (such as Bengay) to treat joint...
Sanskrit writers describe the root as emetic, laxative, stomachic, and rubefacient; they prescribe it in rheumatism, nervous diseases, piles, etc. The leaves...
RUB A535 (also known as Antiphlogistine) is a rubefacient introduced in 1919 and manufactured by Church & Dwight in Montreal, Quebec, Canada. While little...
hypertension, and dysentery. It is also used as a fungicide, dentifrice, rubefacient, diaphoretic, perfume, carminative and sudorific. Before the twentieth...
skin to provoke inflammation. An agent thus used was considered to be a rubefacient (something that causes redness), used as a folk remedy for treating rheumatism...
within the muscle of the area they are applied to, typically acting as rubefacients via a counterirritant effect. Methyl salicylate, which is the analgesic...
arthritis, backache, strains and sprains, often in compounds with other rubefacients. It is also used to reduce the symptoms of peripheral neuropathy, such...
employed as a treatment for headaches and rheumatism and has been used as a rubefacient. Furthermore, the bark is used as a(n) carminative, stimulant, astringent...
large amounts of seed. Drosera burmanni has been considered a powerful rubefacient in Ayurveda. Drosera burmanni is an herb that produces very short stems...
S.; Wiffen, P. J. (2004). "Systematic review of efficacy of topical rubefacients containing salicylates for the treatment of acute and chronic pain"....
used are now considered archaic, such as abasia, astasia, errhines and rubefacients - sternutatories, and many of the agents listed are now not considered...
application in folk medicine for the treatment of rheumatic pain, as laxative, rubefacient and external remedy for ring worm (Kirtikar, 1972). This plant was found...
anaesthetic in the form of a topical cream, or with laurilsulfate in rubefacient preparations. It is used to treat muscle strains, tendinitis or ligament...
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