Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references
Chemical compound
Rhapontigenin is a stilbenoid. It can be isolated from Vitis coignetiae or from Gnetum cleistostachyum.[1]
It shows an action on prostate cancer cells.[2] It has been shown to inhibit the human cytochrome P450 1A1,[3] an enzyme implicated in the biotransformation of a number of carcinogenic and immunotoxic compounds.
Injected in rats, rhapontigenin shows a rapid glucuronidation and a poor bioavailability.[4]
^Stilbenes from Gnetum cleistostachyum. Yao Chun-Suo, Lin Mao, LIiu Xin and Wang Ying-Hong, Huaxue xuebao, 2003, volume 61, no 8, pages 1331-1334, INIST15332136
^Jung, D. B.; Lee, H. J.; Jeong, S. J.; Lee, H. J.; Lee, E. O.; Kim, Y. C.; Ahn, K. S.; Chen, C. Y.; Kim, S. H. (2011). "Rhapontigenin inhibited hypoxia inducible factor 1 alpha accumulation and angiogenesis in hypoxic PC-3 prostate cancer cells". Biological & Pharmaceutical Bulletin. 34 (6): 850–855. doi:10.1248/bpb.34.850. PMID 21628883.
^Chun, Y. J.; Ryu, S. Y.; Jeong, T. C.; Kim, M. Y. (2001). "Mechanism-based inhibition of human cytochrome P450 1A1 by rhapontigenin". Drug Metabolism and Disposition. 29 (4 Pt 1): 389–393. PMID 11259321.
^Roupe, K. A.; Yáñez, J. A.; Teng, X. W.; Davies, N. M. (2006). "Pharmacokinetics of selected stilbenes: Rhapontigenin, piceatannol and pinosylvin in rats". Journal of Pharmacy and Pharmacology. 58 (11): 1443–1450. doi:10.1211/jpp.58.11.0004. PMID 17132206. S2CID 9538085.
Rhapontigenin is a stilbenoid. It can be isolated from Vitis coignetiae or from Gnetum cleistostachyum. It shows an action on prostate cancer cells. It...
Rhaponticin is a stilbenoid glucoside compound. Its aglycone is called rhapontigenin. It can be found in rhubarb rhizomes. It has beneficial effects on diabetic...
bark of Boswellia dalzielii Rhaponticin a glucoside of the stilbenoid rhapontigenin, found in rhubarb rhizomes Phenolic compounds in wine Polyphenol antioxidant...
stilbenoid Lunularic acid, a dihydrostilbenoid Plicatol C, a phenanthrene Rhapontigenin, a stilbenoid Yangonin, a kavalactone Lomatiol, a quinone pigment found...
tetrahydroxylated stilbenoid with a methoxy group. It is an isomer of rhapontigenin and an analog of resveratrol. It is found in the Chinese herb Gnetum...
(2-methoxyoxyresveratrol), gnetucleistol E (3-methoxy-isorhapontigenin), rhapontigenin, isorhapontigenin, 4-methoxyresveratrol and pinosylvin can be found...
Wei; Davies, Neal M. (2006). "Pharmacokinetics of selected stilbenes: Rhapontigenin, piceatannol and pinosylvin in rats". Journal of Pharmacy and Pharmacology...
Neal M. (November 2006). "Pharmacokinetics of selected stilbenes: rhapontigenin, piceatannol and pinosylvin in rats". The Journal of Pharmacy and Pharmacology...