RIT1 information

RIT1
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	4KLZ
Identifiers
Aliases	RIT1, NS8, RIBB, RIT, ROC1, Ras like without CAAX 1
External IDs	OMIM: 609591 MGI: 108053 HomoloGene: 56003 GeneCards: RIT1
Gene location (Human)
Chr.	Chromosome 1 (human)
End	155,911,404 bp
Gene location (Mouse)
Chr.	Chromosome 3 (mouse)
End	88,638,356 bp
RNA expression pattern
	Top expressed in
	monocyte; ; amniotic fluid; ; Achilles tendon; ; stromal cell of endometrium; ; islet of Langerhans; ; blood; ; vagina; ; palpebral conjunctiva; ; ganglionic eminence; ; gallbladder;
	Top expressed in
	saccule; ; seminal vesicula; ; lip; ; ectoderm; ; esophagus; ; lacrimal gland; ; otic placode; ; right lung lobe; ; endocardial cushion; ; blood;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	nucleotide binding; protein binding; calmodulin binding; GTP binding; GTPase activity; GDP binding;
Cellular component	membrane; plasma membrane; intracellular anatomical structure;
Biological process	Ras protein signal transduction; signal transduction;
	Sources:Amigo / QuickGO
Orthologs
	6016
	19769
	ENSG00000143622
	ENSMUSG00000028057
	Q92963
	P70426
	NM_006912; NM_001256820; NM_001256821
	NM_001163310; NM_009069
	NP_001243749; NP_001243750; NP_008843
NP_001156782; NP_033095; NP_001390950; NP_001390951; NP_001390958;
	NP_001390959; NP_001390960; NP_001390962; NP_001390963; NP_001390964; NP_001390965
	Wikidata
View/Edit Human	View/Edit Mouse

GTP-binding protein Rit1 is a protein that in humans is encoded by the RIT1 gene.^[5]^[6]^[7]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000143622 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000028057 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Lee CH, Della NG, Chew CE, Zack DJ (November 1996). "Rin, a neuron-specific and calmodulin-binding small G-protein, and Rit define a novel subfamily of ras proteins". The Journal of Neuroscience. 16 (21): 6784–94. doi:10.1523/JNEUROSCI.16-21-06784.1996. PMC 6579259. PMID 8824319.
^ Wes PD, Yu M, Montell C (November 1996). "RIC, a calmodulin-binding Ras-like GTPase". The EMBO Journal. 15 (21): 5839–48. doi:10.1002/j.1460-2075.1996.tb00971.x. PMC 452332. PMID 8918462.
^ "Entrez Gene: RIT1 Ras-like without CAAX 1".

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