RBBP6 information

RBBP6
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	2C7H, 2YSA, 2YUR, 3ZTG
Identifiers
Aliases	RBBP6, MY038, P2P-R, PACT, RBQ-1, SNAMA, retinoblastoma binding protein 6, RB binding protein 6, ubiquitin ligase
External IDs	OMIM: 600938 MGI: 894835 HomoloGene: 136812 GeneCards: RBBP6
Gene location (Human)
Chr.	Chromosome 16 (human)
End	24,572,863 bp
Gene location (Mouse)
Chr.	Chromosome 7 (mouse)
End	122,601,780 bp
RNA expression pattern
	Top expressed in
	sperm; ; gastric mucosa; ; right uterine tube; ; skin of abdomen; ; cerebellar hemisphere; ; left uterine tube; ; monocyte; ; right lung; ; anterior pituitary; ; Achilles tendon;
	Top expressed in
	medullary collecting duct; ; thymus; ; spermatid; ; plantaris muscle; ; renal corpuscle; ; dorsomedial hypothalamic nucleus; ; supraoptic nucleus; ; motor neuron; ; habenula; ; hair follicle;
	More reference expression data
	; ; ; ;
	More reference expression data
Gene ontology
Molecular function	protein binding; zinc ion binding; nucleic acid binding; metal ion binding; ubiquitin-protein transferase activity; ubiquitin protein ligase activity; transferase activity; RNA binding; protein kinase binding;
Cellular component	nucleolus; microtubule organizing center; nucleus; chromosome; cytoplasm; cytoskeleton; cytosol; centrosome; nuclear speck; protein-containing complex;
Biological process	in utero embryonic development; embryonic organ development; regulation of DNA replication; DNA replication; cellular response to DNA damage stimulus; protein ubiquitination; multicellular organism growth; somite development; mRNA processing; protein polyubiquitination; ubiquitin-dependent protein catabolic process;
	Sources:Amigo / QuickGO
Orthologs
	5930
	19647
	ENSG00000122257
	ENSMUSG00000030779
	Q7Z6E9
	P97868
	NM_006910; NM_018703; NM_032626
	NM_011247; NM_175023
	NP_008841; NP_061173; NP_116015
	NP_035377; NP_778188; NP_001390011; NP_001390012
	Wikidata
View/Edit Human	View/Edit Mouse

Retinoblastoma-binding protein 6 is a protein that in humans is encoded by the RBBP6 gene.^[5]^[6]^[7]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000122257 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000030779 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Sakai Y, Saijo M, Coelho K, Kishino T, Niikawa N, Taya Y (Nov 1995). "cDNA sequence and chromosomal localization of a novel human protein, RBQ-1 (RBBP6), that binds to the retinoblastoma gene product". Genomics. 30 (1): 98–101. doi:10.1006/geno.1995.0017. PMID 8595913.
^ Pugh DJ, Ab E, Faro A, Lutya PT, Hoffmann E, Rees DJ (Feb 2006). "DWNN, a novel ubiquitin-like domain, implicates RBBP6 in mRNA processing and ubiquitin-like pathways". BMC Structural Biology. 6: 1. doi:10.1186/1472-6807-6-1. PMC 1360078. PMID 16396680.
^ "Entrez Gene: RBBP6 retinoblastoma binding protein 6".

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000122257 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000030779 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid8595913-5] Sakai Y, Saijo M, Coelho K, Kishino T, Niikawa N, Taya Y (Nov 1995). "cDNA sequence and chromosomal localization of a novel human protein, RBQ-1 (RBBP6), that binds to the retinoblastoma gene product". Genomics. 30 (1): 98–101. doi:10.1006/geno.1995.0017. PMID 8595913.

[pmid16396680-6] Pugh DJ, Ab E, Faro A, Lutya PT, Hoffmann E, Rees DJ (Feb 2006). "DWNN, a novel ubiquitin-like domain, implicates RBBP6 in mRNA processing and ubiquitin-like pathways". BMC Structural Biology. 6: 1. doi:10.1186/1472-6807-6-1. PMC 1360078. PMID 16396680.

[entrez-7] "Entrez Gene: RBBP6 retinoblastoma binding protein 6".

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