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Purpura information


Purpura
Petechiae and purpura on the lower limb due to medication-induced vasculitis
SpecialtyDermatology, hematology

Purpura (/ˈpɜːrpjʊərə/[1]) is a condition of red or purple discolored spots on the skin that do not blanch on applying pressure. The spots are caused by bleeding underneath the skin secondary to platelet disorders, vascular disorders, coagulation disorders, or other causes.[2] They measure 3–10 mm,[3] whereas petechiae measure less than 3 mm, and ecchymoses greater than 1 cm.[4]

Purpura is common with typhus and can be present with meningitis caused by meningococci or septicaemia. In particular, meningococcus (Neisseria meningitidis), a Gram-negative diplococcus organism, releases endotoxin when it lyses. Endotoxin activates the Hageman factor (clotting factor XII), which causes disseminated intravascular coagulation (DIC). The DIC is what appears as a rash on the affected individual.

  1. ^ "PURPURA English Definition and Meaning | Lexico.com". Archived from the original on October 17, 2019.
  2. ^ "UCSF Purpura Module" (PDF). Archived from the original (PDF) on 2013-10-02.
  3. ^ McKenzie, Shirlyn B. (2014). Clinical Laboratory Hematology. Williams, Joanne Lynne; Landis-Piwowar, Kristin (3rd ed.). Boston. p. 665. ISBN 978-0133076011. OCLC 878098857.{{cite book}}: CS1 maint: location missing publisher (link)
  4. ^ Robbins basic pathology. Kumar, Vinay; Abbas, Abul K.; Aster, Jon C.; Perkins, James A. (10th ed.). Philadelphia, Pennsylvania. 2017-03-28. p. 101. ISBN 978-0323353175. OCLC 960844656.{{cite book}}: CS1 maint: location missing publisher (link) CS1 maint: others (link)

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Purpura

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purpura) Primary thrombocytopenic purpura Secondary thrombocytopenic purpura Post-transfusion purpura Vascular disorders (nonthrombocytopenic purpura)...

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Thrombotic thrombocytopenic purpura

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Thrombotic thrombocytopenic purpura (TTP) is a blood disorder that results in blood clots forming in small blood vessels throughout the body. This results...

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Immune thrombocytopenic purpura

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thrombocytopenic purpura (ITP), also known as idiopathic thrombocytopenic purpura or immune thrombocytopenia, is a type of thrombocytopenic purpura characterized...

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Thrombocytopenic purpura

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Thrombocytopenic purpura are purpura associated with a reduction in circulating blood platelets which can result from a variety of causes, such as kaposi...

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Thrombocytopenia

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heavier or longer periods or breakthrough bleeding. Bruising, particularly purpura in the forearms and petechiae in the feet, legs, and mucous membranes,...

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Purpura fulminans

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Purpura fulminans is an acute, often fatal, thrombotic disorder which manifests as blood spots, bruising and discolouration of the skin resulting from...

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Solar purpura

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Solar purpura (also known as "Actinic purpura," and "Senile purpura") is a skin condition characterized by large, sharply outlined, 1- to 5-cm, dark purplish-red...

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Palpable purpura

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Palpable purpura is characterized by firm, elevated hemorrhagic plaques or papules that can measure several centimeters in diameter. These are typically...

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Nonthrombocytopenic purpura

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Nonthrombocytopenic purpura is a type of purpura (red or purple skin discoloration) not associated with thrombocytopenia. Nonthrombocytopenic purpura has been reported...

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Purpura haemorrhagica

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Purpura haemorrhagica is a rare complication of equine strangles and is caused by bleeding from capillaries which results in red spots on the skin and...

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Retiform purpura

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Retiform purpura is the result of total vascular blockage and damage to the skin's blood vessels. The skin then shows lesions, appearing due to intravascular...

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Amyloid purpura

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Amyloid purpura is a condition marked by bleeding under the skin (purpura) in some individuals with amyloidosis. Its cause is unknown, but coagulation...

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Dog whelk

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theobroma Roding, 1798 Purpura buccinoidea Blainville, 1829 Purpura imbricata Lamarck, 1822 Purpura lapillus (Linnaeus, 1758) Purpura lapillus var. anomala...

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Petechia

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differentiated by size, the other two being ecchymosis (>1cm in diameter) and purpura (4-10mm in diameter). The term is typically used in the plural (petechiae)...

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Schamberg disease

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"progressive pigmentary dermatosis of Schamberg", "purpura pigmentosa progressiva" (PPP), and "Schamberg's purpura") is a chronic discoloration of the skin found...

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Pigmented purpuric dermatosis

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eruptions. Pigmented purpuric dermatosis are distinguished from other purpura by size (0.3–1 cm) and are most often seen in the lower extremities.: 829 ...

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Schistocyte

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heart valves, hemolytic uremic syndrome, and thrombotic thrombocytopenic purpura, among other causes. Excessive schistocytes present in blood can be a sign...

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Shades of purple

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name of the color that in Latin is denominated "purpura". Other contemporary English names for purpura are "imperial purple" and "royal purple". The English...

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Bruise

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such as cytomegalovirus); and purpura (3–10 mm (0.12–0.39 in)), classified as palpable purpura or non-palpable purpura and indicating various pathologic...

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Doucas and Kapetanakis pigmented purpura

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Doucas and Kapetanakis pigmented purpura is a skin condition characterized by scaly and eczematous patches, which also have petechiae and hemosiderin...

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The Purple Network

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The Purple Network (Spanish: La red púrpura) is a Spanish neo-noir thriller television miniseries created, co-directed and executively produced by Paco...

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Stramonita haemastoma

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Salinas. Palermo, Muratori 54 p Reeve, L. A. (1846). Monograph of the genus Purpura. In: Conchologia iconica, or, illustrations of the shells of molluscous...

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Orthostatic purpura

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Orthostatic purpura is a skin condition that results from prolonged standing or even sitting with the legs lowered (as in a bus, airplane, or train),...

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Chickenpox

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described: febrile purpura, malignant chickenpox with purpura, postinfectious purpura, purpura fulminans, and anaphylactoid purpura. These syndromes have...

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Cryoglobulinemia

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description of cryoglobulinemia in association with the clinical triad of skin purpura, joint pain, and weakness by Meltzer et al. in 1967, the percentage of...

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