PP1 plays an instrumental role in glycogen metabolism through its responsibility for the interconversion between phosphorylase a and b.
Protein phosphatase 1 (PP1) belongs to a certain class of phosphatases known as protein serine/threonine phosphatases. This type of phosphatase includes metal-dependent protein phosphatases (PPMs) and aspartate-based phosphatases. PP1 has been found to be important in the control of glycogen metabolism, muscle contraction, cell progression, neuronal activities, splicing of RNA, mitosis,[1] cell division, apoptosis, protein synthesis, and regulation of membrane receptors and channels.[2]
^Tournebize R, Andersen SS, Verde F, Dorée M, Karsenti E, Hyman AA (September 1997). "Distinct roles of PP1 and PP2A-like phosphatases in control of microtubule dynamics during mitosis". The EMBO Journal. 16 (18): 5537–49. doi:10.1093/emboj/16.18.5537. PMC 1170186. PMID 9312013.
^Fong NM, Jensen TC, Shah AS, Parekh NN, Saltiel AR, Brady MJ (November 2000). "Identification of binding sites on protein targeting to glycogen for enzymes of glycogen metabolism". The Journal of Biological Chemistry. 275 (45): 35034–9. doi:10.1074/jbc.M005541200. PMID 10938087.
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Proteinphosphatase1 (PP1) belongs to a certain class of phosphatases known as protein serine/threonine phosphatases. This type of phosphatase includes...
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subcategory of hydrolases. Phosphatase enzymes are essential to many biological functions, because phosphorylation (e.g. by protein kinases) and dephosphorylation...
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Tyrosine-proteinphosphatase non-receptor type 1 also known as protein-tyrosine phosphatase 1B (PTP1B) is an enzyme that is the founding member of the protein...
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Proteinphosphatase1 regulatory subunit 7 is an enzyme that in humans is encoded by the PPP1R7 gene. GRCh38: Ensembl release 89: ENSG00000115685 – Ensembl...
the three catalytic subunits of proteinphosphatase1 (PP1). PP1 is a serine/threonine specific proteinphosphatase known to be involved in the regulation...
Protein Arginine Phosphatase (PAPs), also known as Phosphoarginine Phosphatase, is an enzyme that catalyzes the dephosphorylation of phosphoarginine residues...
Proteinphosphatase inhibitor 2 is an enzyme that in humans is encoded by the PPP1R2 gene. PPP1R2 has been shown to interact with LMTK2 and PPP1R9B. GRCh38:...
Alkaline Phosphatase Is Irreversibly Transformed into an Inactive Dimer by Low Urea Concentrations.” Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics...
catalyzed by proteinphosphatases. Protein kinases and phosphatases work independently and in a balance to regulate the function of proteins. The amino...
Elevated alkaline phosphatase occurs when levels of alkaline phosphatase (ALP) exceed the reference range. This group of enzymes has a low substrate specificity...
Phosphatase and actin regulator 1 (PHACTR1) is a protein that in humans is encoded by the PHACTR1 gene on chromosome 6. It is most significantly expressed...
Proteinphosphatase1 regulatory subunit 12A is an enzyme that in humans is encoded by the PPP1R12A gene. Myosin phosphatase target subunit 1, which is...
Proteinphosphatase1 regulatory subunit 11 is an enzyme that in humans is encoded by the PPP1R11 gene. This gene encodes a specific inhibitor of protein...
Dual specificity proteinphosphatase1 is an enzyme that in humans is encoded by the DUSP1 gene. The expression of DUSP1 gene is induced in human skin...
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