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Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Chemical compound
Pregnane, also known as 17β-ethylandrostane or as 10β,13β-dimethyl-17β-ethylgonane, is a C21 steroid and, indirectly, a parent of progesterone. It is a parent hydrocarbon for two series of steroids stemming from 5α-pregnane (originally allopregnane) and 5β-pregnane (17β-ethyletiocholane). It has a gonane core.
5β-Pregnane is the parent of pregnanediones, pregnanolones, and pregnanediols, and is found largely in urine as a metabolic product of 5β-pregnane compounds.
^International Union of Pure and Applied Chemistry (2014). Nomenclature of Organic Chemistry: IUPAC Recommendations and Preferred Names 2013. The Royal Society of Chemistry. p. 1530. doi:10.1039/9781849733069. ISBN 978-0-85404-182-4.
steroids stemming from 5α-pregnane (originally allopregnane) and 5β-pregnane (17β-ethyletiocholane). It has a gonane core. 5β-Pregnane is the parent of pregnanediones...
virilization of the male fetus. Allopregnanolone is an endogenous inhibitory pregnane neurosteroid. It is made from pregnenolone, and is a positive allosteric...
In the field of molecular biology, the pregnane X receptor (PXR), also known as the steroid and xenobiotic sensing nuclear receptor (SXR) or nuclear receptor...
lactation or with infants due to its toxins, which include resinoids and pregnanes. Native Americans and European pioneers used the boiled roots to treat...
serves as a skeleton. These parent structures have specific names, such as pregnane, androstane, etc. The derivatives carry various functional groups called...
Allopregnanediol, or 5α-pregnane-3α,20α-diol, is an endogenous metabolite of progesterone and allopregnanolone and an isomer of pregnanediol (5β-pregnan-3α...
2817 u) may refer to: Allopregnane, or 5α-PregnanePregnane, also known as 17β-ethylandrostane 5β-Pregnane This set index page lists chemical structure...
common forms include 5α-gonane and 5β-gonane. Estrane, androstane, and pregnane are variants of gonane with additional methyl or ethyl groups attached...
progestogens are characterized by their basic 21-carbon skeleton, called a pregnane skeleton (C21). In similar manner, the estrogens possess an estrane skeleton...
Allopregnane, also known as 5α-pregnane or as 10β,13β-dimethyl-17β-ethyl-5α-gonane, is a steroid and a parent compound of a variety of steroid derivatives...
Pregnanedione, or pregnane-3,20-dione, may refer to: 5α-Dihydroprogesterone (5α-pregnane-3,20-dione) 5β-Dihydroprogesterone (5β-pregnane-3,20-dione) Progesterone...
its elimination half-life would suggest. Triamcinolone is a synthetic pregnane corticosteroid and derivative of cortisol (hydrocortisone) and is also...
cyclic 16,17-acetal with acetone, is a synthetic halogenated cyclic ketal pregnane corticosteroid. It is the C16α,17α acetonide of triamcinolone. Triamcinolone...
such as estradiol, estrone, and estriol are estratrienes. Androstane Pregnane International Union of Pure and Applied Chemistry (2014). Nomenclature...
nasopharyngitis, and urinary tract infection. An orally active inhibitory pregnane neurosteroid, zuranolone acts as a positive allosteric modulator of the...
[citation needed] It has been found to act as an agonist of the human pregnane X receptor ligand-binding domain and to induce CYP3A4 expression in vitro...
derivatives with carbons present at positions 1 through 19. Estrane and pregnane C19H32 Wilson JD (1996). "Role of dihydrotestosterone in androgen action"...
neuroprotective antioxidant that scavenges hydroxyl radicals. IPA binds to the pregnane X receptor (PXR) in intestinal cells, thereby facilitating mucosal homeostasis...
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