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Portal vein information


Portal vein
The portal vein (in light blue) and its tributaries. It is formed by the superior mesenteric vein, inferior mesenteric vein, and splenic vein. Lienal vein is an old term for splenic vein.
Details
SystemHepatic portal system
Drains fromGastrointestinal tract, spleen, pancreas
Sourcesplenic vein, superior mesenteric vein, inferior mesenteric vein, pancreatic vein
Drains toliver sinusoid
Identifiers
Latinvena portae hepatis
MeSHD011169
TA98A12.3.12.001
TA25092
FMA50735
Anatomical terminology
[edit on Wikidata]

The portal vein or hepatic portal vein (HPV) is a blood vessel that carries blood from the gastrointestinal tract, gallbladder, pancreas and spleen to the liver. This blood contains nutrients and toxins extracted from digested contents. Approximately 75% of total liver blood flow is through the portal vein, with the remainder coming from the hepatic artery proper. The blood leaves the liver to the heart in the hepatic veins.

The portal vein is not a true vein, because it conducts blood to capillary beds in the liver and not directly to the heart. It is a major component of the hepatic portal system, one of three portal venous systems in the human body; the others being the hypophyseal and renal portal systems.

The portal vein is usually formed by the confluence of the superior mesenteric, splenic veins, inferior mesenteric, left, right gastric veins and the pancreatic vein.

Conditions involving the portal vein cause considerable illness and death. An important example of such a condition is elevated blood pressure in the portal vein. This condition, called portal hypertension, is a major complication of cirrhosis. In abdominal obesity fats, inflammatory cytokines and other toxic substances are transported by the portal vein from visceral fat into the liver, leading to hepatic insulin resistance and non-alcoholic fatty liver disease.[1][2]

  1. ^ Item F, Konrad D (2012). "Visceral fat and metabolic inflammation: the portal theory revisited" (PDF). Obesity Reviews. 13 (Suppl 2): 30–39. doi:10.1111/j.1467-789X.2012.01035.x. PMID 23107257. S2CID 25169877.
  2. ^ Dhawan D, Sharma S (2020). "Abdominal Obesity, Adipokines and Non-communicable Diseases". The Journal of Steroid Biochemistry and Molecular Biology. 203: 105737. doi:10.1016/j.jsbmb.2020.105737. PMC 7431389. PMID 32818561.

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Hepatic portal system

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the hepatic portal system or portal venous system is the system of veins comprising the portal vein and its tributaries. The other portal venous systems...

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through veins Hepatic portal system, the portal system between the digestive system and the liver Hepatic portal vein, a vein that drains blood from...

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circulatory system of vertebrates, a portal venous system occurs when a capillary bed pools into another capillary bed through veins, without first going through...

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Liver

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artery and the portal vein. The hepatic artery carries oxygen-rich blood from the aorta via the celiac trunk, whereas the portal vein carries blood rich...

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Portal hypertension

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hypertension is present at portal pressures greater than 10 mmHg. The portal vein and its branches supply most of the blood and nutrients from the intestine...

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Renal portal system

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renal portal vein in mammals. In lungfish and tetrapods, the renal portal vein is joined by a vein traveling upwards from the abdominal vein, which can...

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Thrombosis

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intervention by the use of shunts. Portal vein thrombosis affects the hepatic portal vein, which can lead to portal hypertension and reduction of the blood...

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Hepatic veins

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the hepatic veins are the veins that drain venous blood from the liver into the inferior vena cava (as opposed to the hepatic portal vein which conveys...

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Superior mesenteric vein

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superior mesenteric vein combines with the splenic vein to form the portal vein that carries blood to the liver. The superior mesenteric vein lies to the right...

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Inferior mesenteric vein

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goes on to form the portal vein with the superior mesenteric vein (SMV). The inferior mesenteric vein merges with the splenic vein, posterior to the middle...

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Circulatory system

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into veins leading back to the heart. Portal veins are a slight exception to this. In humans, the only significant example is the hepatic portal vein which...

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Splenic vein

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mesenteric vein) via the inferior mesenteric vein, which drains in the splenic vein shortly before the origin of the hepatic portal vein. The splenic vein ends...

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Portal venous pressure

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Portal venous pressure is the blood pressure in the hepatic portal vein, and is normally between 5-10 mmHg. Raised portal venous pressure is termed portal...

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Cirrhosis

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paraumbilical collateral veins due to portal hypertension. Blood from the portal venous system may be forced through the paraumbilical veins and ultimately to...

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Transjugular intrahepatic portosystemic shunt

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establishes communication between the inflow portal vein and the outflow hepatic vein. It is used to treat portal hypertension (which is often due to liver...

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Lobules of liver

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liver tissue, consisting of a portal triad, hepatocytes arranged in linear cords between a capillary network, and a central vein. Lobules are different from...

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Round ligament of liver

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umbilical vein degenerates to fibrous tissue. The left portal vein (which gives branches to paraumbilical veins) is connected to the round ligament (ligamentum...

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Pylephlebitis

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Pylephlebitis is an uncommon thrombophlebitis of the portal vein or any of its branches (i.e. a portal vein thrombosis) that is caused by infection. It is usually...

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First pass effect

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absorbed by the digestive system and enters the hepatic portal system. It is carried through the portal vein into the liver before it reaches the rest of the...

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Right gastric vein

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right gastric vein (pyloric vein) drains blood from the lesser curvature of the stomach into the hepatic portal vein. It is part of the portal circulation...

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Varicose veins

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Caput medusae

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venomous snakes in place of hair. It is also a sign of portal hypertension. When the portal vein, that transfers the blood from the gastrointestinal tract...

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Ductus venosus

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circulation. The pathway of fetal umbilical venous flow is umbilical vein to left portal vein to ductus venosus to inferior vena cava and eventually the right...

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