This child presented with seizures. The coronal true inversion recovery sequence shows thickened and disordered cortex in superior frontal and cingulate gyri bilaterally (arrow). There are small convolutions visible at the corticomedullary junction. The appearance is that of cortical dysplasia, with polymicrogyria more likely than pachygyria due to the small convolutions visible. There are also small foci of grey matter signal in the corpus callosum, deep to the dysplastic cortex (double arrows). These probably represent areas of grey matter heterotopia.
Specialty
Neurology
Polymicrogyria (PMG) is a condition that affects the development of the human brain by multiple small gyri (microgyri) creating excessive folding of the brain leading to an abnormally thick cortex. This abnormality can affect either one region of the brain or multiple regions.
The time of onset has yet to be identified; however, it has been found to occur before birth in either the earlier or later stages of brain development. Early stages include impaired proliferation and migration of neuroblasts, while later stages show disordered post-migration development.
The symptoms experienced differ depending on what part of the brain is affected. There is no specific treatment to get rid of this condition, but there are medications that can control the symptoms such as seizures, delayed development or weakened muscles as some of the noted effects.
Polymicrogyria (PMG) is a condition that affects the development of the human brain by multiple small gyri (microgyri) creating excessive folding of the...
Bilateral frontoparietal polymicrogyria is a genetic disorder with autosomal recessive inheritance that causes a cortical malformation. Our brain has folds...
megalencephaly-capillary malformation (MCAP) and megalencephaly-polydactyly-polymicrogyria-hydrocephalus (MPPH). Megalencephaly is usually diagnosed at birth and...
with various diseases and disorders. Pachygyria, lissencephaly, and polymicrogyria are all the results of abnormal cell migration associated with a disorganized...
brain with a thicker cortex will have a lesser degree of gyrification. Polymicrogyria is a condition in which the brain has an overly convoluted cortex. Though...
channels and pumps can be associated with the same disease. For instance, polymicrogyria has been associated with the channel gene SCN3A and the pump gene ATP1A3...
often confused with a similar distortion of the cortex known as polymicrogyria. Polymicrogyria is characterized by excessive folding of the surface gyri and...
BFPP may refer to: Bilateral frontoparietal polymicrogyria, genetic disease GPR56, GPCR Bulletin Français de la Pêche et de la Pisciculture This disambiguation...
described the Kuzniecky Syndrome in 1991, also known as perisylvian polymicrogyria. The syndrome is characterized by seizures, cognitive abnormalities...
formation of the cerebral cortex include microgyria, polymicrogyria, bilateral frontoparietal polymicrogyria, and pachygyria. A tumor is an abnormal growth...
malformation, hydrocephalus, microencephaly, megalencephaly, lissencephaly, polymicrogyria, holoprosencephaly, and agenesis of the corpus callosum. Congenital...
Politico-Military Group, a body of the Council of the European Union Polymicrogyria Ponta Porã International Airport, Brazil Postmaster General (disambiguation)...
children. Schuller's son Cohen has a chronic rare brain disease called polymicrogyria which causes epilepsy and intellectual delay. Crystal Cathedral Ministries...
spectrum disorder MRI findings Diffuse polymicrogyria Typically normal Corpus callosum hypoplasia Polymicrogyria Hippocampal dysplasia Typically normal...
cause a severe cortical malformation known as bilateral frontoparietal polymicrogyria (BFPP). Investigating the pathological mechanism of disease-associated...
syndrome-faciodigital anomaly syndrome Poikiloderma with neutropenia Polymicrogyria with or without vascular-type Ehlers-Danlos syndrome Pontocerebellar...
ventricular arrhythmia caused by voltage-gated sodium channel gene mutations. Polymicrogyria is a developmental brain malformation caused by voltage-gated sodium...
infantile spasms. Other types of defects of the brain such as microcephaly, polymicrogyria, porencephalic cysts and enlarged cerebral ventricles due to hydrocephalus...
interpreted cautiously since even experienced radiologists can misdiagnose polymicrogyria, a different developmental malformation of the brain, as lissencephaly...
in GRIN2B and GRIN1 associated with cortical malformations, such as polymicrogyria. D-serine, an antagonist/inverse co-agonist of t-NMDA receptors, which...
include: Brain malformation syndromes, including lissencephaly and polymicrogyria Brain tumor predisposition syndromes, including Neurofibromatosis 1...
system disorders which are associated with colpocephaly are as follows: polymicrogyria Periventricular leukomalacia (PVL) intraventricular hemorrhage Hydrocephalus...
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