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Plate readers, also known as microplate readers or microplate photometers, are instruments which are used to detect biological, chemical or physical events of samples in microtiter plates. They are widely used in research, drug discovery,[1] bioassay validation, quality control and manufacturing processes in the pharmaceutical and biotechnological industry and academic organizations. Sample reactions can be assayed in 1-1536 well format microtiter plates. The most common microplate format used in academic research laboratories or clinical diagnostic laboratories is 96-well (8 by 12 matrix) with a typical reaction volume between 100 and 200 μL per well. Higher density microplates (384- or 1536-well microplates) are typically used for screening applications, when throughput (number of samples per day processed) and assay cost per sample become critical parameters, with a typical assay volume between 5 and 50 μL per well. Common detection modes for microplate assays are absorbance, fluorescence intensity, luminescence, time-resolved fluorescence, and fluorescence polarization.
^Neves, Bruno Junior; Agnes, Jonathan Paulo; Gomes, Marcelo do Nascimento; Henriques Donza, Marcio Roberto; Gonçalves, Rosângela Mayer; Delgobo, Marina; Ribeiro de Souza Neto, Lauro; Senger, Mario Roberto; Silva-Junior, Floriano Paes; Ferreira, Sabrina Baptista; Zanotto-Filho, Alfeu; Andrade, Carolina Horta (March 2020). "Efficient identification of novel anti-glioma lead compounds by machine learning models". European Journal of Medicinal Chemistry. 189: 111981. doi:10.1016/j.ejmech.2019.111981. PMID 31978780. S2CID 210892159.
Platereaders, also known as microplate readers or microplate photometers, are instruments which are used to detect biological, chemical or physical events...
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ISBN 978-0-486-64235-2. "Spreading Liquid Cultures of Bacteria on Agar-Media Plates" (PDF). chemistry.ucla.edu. Archived (PDF) from the original on 2022-10-09...
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