LCP1 information

LCP1
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	2D85
Identifiers
Aliases	LCP1, CP64, HEL-S-37, L-PLASTIN, LC64P, LPL, PLS2, lymphocyte cytosolic protein 1
External IDs	OMIM: 153430; MGI: 104808; HomoloGene: 80174; GeneCards: LCP1; OMA:LCP1 - orthologs
Gene location (Human)
Chr.	Chromosome 13 (human)
End	46,211,871 bp
Gene location (Mouse)
Chr.	Chromosome 14 (mouse)
End	75,468,282 bp
RNA expression pattern
	Top expressed in
	monocyte; ; granulocyte; ; blood; ; bone marrow cells; ; spleen; ; appendix; ; corpus epididymis; ; trabecular bone; ; gallbladder; ; right lung;
	Top expressed in
	granulocyte; ; spleen; ; tibiofemoral joint; ; mesenteric lymph nodes; ; thymus; ; stroma of bone marrow; ; yolk sac; ; parotid gland; ; blood; ; seminal vesicula;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	calcium ion binding; metal ion binding; actin filament binding; identical protein binding; GTPase binding; actin binding; integrin binding;
Cellular component	cytoplasm; cytosol; cell projection; membrane; focal adhesion; filopodium; ruffle; plasma membrane; stress fiber; ruffle membrane; actin filament; actin cytoskeleton; actin filament bundle; podosome; phagocytic cup; extracellular exosome; cytoskeleton; extracellular space; cell junction; perinuclear region of cytoplasm;
Biological process	extracellular matrix disassembly; positive regulation of podosome assembly; actin filament bundle assembly; regulation of intracellular protein transport; animal organ regeneration; protein kinase A signaling; cell migration; wound healing, spreading of cells; T cell activation involved in immune response; actin filament network formation; actin crosslink formation; interleukin-12-mediated signaling pathway;
	Sources:Amigo / QuickGO
Orthologs
	3936
	18826
	ENSG00000136167
	ENSMUSG00000021998
	P13796
	Q61233
	NM_002298
	NM_001247984; NM_008879
	NP_002289; NP_002289.2
	NP_001234913; NP_032905
	Wikidata
View/Edit Human	View/Edit Mouse

Plastin-2 is a protein that in humans is encoded by the LCP1 gene.^[5]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000136167 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000021998 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Zu Y, Kohno M, Kubota I, Nishida E, Hanaoka M, Namba Y (January 1990). "Characterization of interleukin 2 stimulated 65-kilodalton phosphoprotein in human T cells". Biochemistry. 29 (4): 1055–62. doi:10.1021/bi00456a030. PMID 2111166.

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000136167 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000021998 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid2111166-5] Zu Y, Kohno M, Kubota I, Nishida E, Hanaoka M, Namba Y (January 1990). "Characterization of interleukin 2 stimulated 65-kilodalton phosphoprotein in human T cells". Biochemistry. 29 (4): 1055–62. doi:10.1021/bi00456a030. PMID 2111166.

LCP1 information

and 5 Related for: LCP1 information

LCP1

Plastin

EF hand

Calponin homology domain

TOX4