This condition is inherited in an autosomal dominant manner[1]
Specialty
Rheumatology
Plantar fascial fibromatosis, also known as Ledderhose's disease, Morbus Ledderhose, and plantar fibromatosis, is a relatively uncommon[2] non-malignant thickening of the feet's deep connective tissue, or fascia. In the beginning, where nodules start growing in the fascia of the foot, the disease is minor.[citation needed] Over time, walking becomes painful. The disease is named after Georg Ledderhose, a German surgeon who described the condition for the first time in 1894.[3][4] A similar disease is Dupuytren's disease, which affects the hand and causes bent hand or fingers.
As in most forms of fibromatosis, it is usually benign and its onset varies with each patient.[5] The nodules are typically slow growing[2][5] and most often found in the central and medial portions of the plantar fascia.[2] Occasionally, the nodules may lie dormant for months to years only to begin rapid and unexpected growth.[5] Options for intervention include radiation therapy, cryosurgery, treatment with collagenase clostridium histolyticum, or surgical removal only if discomfort hinders walking.[6]
Plantar fascial fibromatosis, also known as Ledderhose's disease, Morbus Ledderhose, and plantarfibromatosis, is a relatively uncommon non-malignant...
response to plantar fasciitis over a period of time. It may also be related to ankylosing spondylitis, typically in children. Plantarfibromatosis is a relatively...
Tentative evidence supports the use of verapamil topically to treat plantarfibromatosis. Verapamil use in people with recent onset type-1 diabetes may improve...
Ledderhose may refer to: Georg Ledderhose (1855–1925), a German surgeon Plantarfibromatosis, also known as Ledderhose's disease Lederhosen This disambiguation...
aggressive) FMTs Palmer/plantar-type fibromatosis, also known as plantar fibroma and Ledderhose disease. Desmoid-type fibromatosis, also termed desmoid tumor...
containing many disulfide bonds. It is the natural reaction of the palmar or plantar skin. Too much friction occurring too fast for the skin to develop a protective...
through the entrance of a skin wound. A number of types exist, including plantar warts, "filiform warts", and genital warts. Genital warts are often sexually...
camptodactyly, epidermolytic palmoplantar keratoderma, Dupuytren's disease, plantarfibromatosis (Ledderhose's disease), and Bart-Pumphrey syndrome are among the...
most famous today for being the first to describe the condition of plantarfibromatosis in 1894, which is now known as Ledderhose's disease in his honor...
particular, that of the ulcerated mucosa.[verification needed] The mechanism of plantar ulceration in leprosy and its treatment was first described by Ernest W...
at the centre of two or more lesions, Two or more lesions on palmar or plantar skin surfaces, and Clinical or serological evidence of secondary syphilis...
size, appearance, and location on the body where they occur. For example, plantar warts (verrucae plantaris), occur on the soles of the feet and appear as...
infancy with a predilection for the hands, feet, and extremities, and palmar-plantar hyperkeratosis and erosions may be present.: 598 : 556 17q12-q21 (KRT5)...
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