Painful bruising syndrome (also known as "autoerythrocyte sensitization", "Gardner–Diamond syndrome", and "psychogenic purpura") is an idiopathic trauma-induced condition seen in young to middle-aged women who sometimes manifest personality disorders.[2]: 829 It is characterized by a distinctive localized purpuric reaction occurring primarily on the legs, face and trunk, with recurring painful ecchymoses variably accompanied by syncope, nausea, vomiting, gastrointestinal and intracranial bleeding.[3]
Patients with this condition can experience frequent painful bruising around joints and muscles. Because of the rarity of the disorder, there are few methods of support in place for patients.[4]
Many patients are labelled with the stigma of having a psychological condition without this having a specifically proven link. There have been cases of painful bruising syndrome reported where there are no additional psychological disorders. This has been known to be put into remission with chemotherapy. It was characterized in 1955 by Frank Gardner and Louis Diamond.[5][6]
Patient may present with a history of intermittent purpura mostly precipitated by stress.[citation needed]
^"Orphanet: Autoerythrocyte sensitization syndrome". www.orpha.net. Retrieved 21 April 2019.
^James, William D.; Berger, Timothy G.; et al. (2006). Andrews' Diseases of the Skin: clinical Dermatology. Saunders Elsevier. ISBN 978-0-7216-2921-6.
^Rapini, Ronald P.; Bolognia, Jean L.; Jorizzo, Joseph L. (2007). Dermatology: 2-Volume Set. St. Louis: Mosby. ISBN 978-1-4160-2999-1.
^Ivanov, OL; Lvov, AN; Michenko, AV; Künzel, J; Mayser, P; Gieler, U (2009). "Autoerythrocyte sensitization syndrome (Gardner-Diamond syndrome): review of the literature**". Journal of the European Academy of Dermatology and Venereology. 23 (5): 499–504. doi:10.1111/j.1468-3083.2009.03096.x. ISSN 0926-9959. PMID 19192020. S2CID 27542376.
^synd/3229 at Who Named It?
^GARDNER FH, DIAMOND LK (July 1955). "Autoerythrocyte sensitization; a form of purpura producing painful bruising following autosensitization to red blood cells in certain women". Blood. 10 (7): 675–90. doi:10.1182/blood.V10.7.675.675. PMID 14389381.
and 26 Related for: Painful bruising syndrome information
Painfulbruisingsyndrome (also known as "autoerythrocyte sensitization", "Gardner–Diamond syndrome", and "psychogenic purpura") is an idiopathic trauma-induced...
have cases of stigmatic priests appeared. One suggestion is that painfulbruisingsyndrome may explain rare cases of non self-induced stigmata. Skeptical...
caused by the use of levamisole as a cutting agent for cocaine. Spontaneous bruising of the earlobes is considered characteristic of this condition, but lesions...
and physiotherapy. Usually chondromalacia develops without swelling or bruising and most individuals benefit from rest and adherence to an appropriate...
published an article claiming that Evolo may have suffered from painfulbruisingsyndrome: It appears quite simple for the reader to understand how the...
imbalance, or a skeletal deformity. The most common underlying cause of a painful limp is physical trauma; however, in the absence of trauma, other serious...
differentiation – these conditions may co-exist. Dercum's disease is a syndrome of painful growths in subcutaneous fat. Unlike lipedema, which occurs primarily...
discovered the blood diseases Gardner–Diamond syndrome, a painfulbruising disorder, and Shwachman–Diamond syndrome, a rare genetic disorder that affects many...
Cutaneous radiation syndrome Epidermolysis bullosa: a genetic disorder that results in a detachment in the skin layers, resulting in easy bruising. Friction blisters...
any need for hospitalization. Some patients may have pain, swelling, or bruising where the lipoma was removed. These symptoms usually subside after a few...
complete loss of function from that vertebra down. A partial severing or even bruising of the spinal cord results in varying degrees of mixed function and paralysis...
are called blasts or leukemia cells. Symptoms may include bleeding and bruising, bone pain, fatigue, fever, and an increased risk of infections. These...
the muscle may be bruised, resulting in pain in the area treated. This bruising may last for one to three days after treatment, and may feel like, but...
particular part of the body. Soft tissue injuries can result in pain, swelling, bruising and loss of function. A sprain is a type of acute injury which results...
motor neurons from oxidative stress. The most common side effects are bruising and gait disturbance. Edaravone is available as an intravenous infusion...
During sexual assault, victims experience physical trauma such as soreness, bruising, pain, genital irritation, genital infection, severe tearing of vaginal...
Possible complications of thoracentesis include the following: Bleeding and bruising where the needle went in. In rare cases, bleeding may occur in or around...
dye laser therapy included mild temporary pain at the site of therapy, bruising (lasting up to 2–3 weeks), and temporary discoloration of the treated skin...
symptoms include fever, headaches, and vomiting, as well as swollen and painful lymph nodes occurring in the area closest to where the bacteria entered...
syndrome, dermatophobia, parasitophobia, formication and "cocaine bugs". Morgellons is a form of delusional parasitosis in which people have painful skin...
Symptoms may include feeling tired, pale skin color, fever, easy bleeding or bruising, enlarged lymph nodes, or bone pain. As an acute leukemia, ALL progresses...