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PTGES3 information


PTGES3
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesPTGES3, P23, TEBP, cPGES, prostaglandin E synthase 3
External IDsOMIM: 607061; MGI: 1929282; HomoloGene: 128197; GeneCards: PTGES3; OMA:PTGES3 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_019766

RefSeq (protein)

NP_062740

Location (UCSC)Chr 12: 56.66 – 56.69 MbChr 10: 127.89 – 127.91 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Prostaglandin E synthase 3 (cytosolic) is an enzyme that in humans is encoded by the PTGES3 gene.[5]

The protein encoded by this gene is also known as p23 which functions as a chaperone which is required for proper functioning of the glucocorticoid and other steroid receptors.[6]

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000110958 – Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000071072 – Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ "Entrez Gene: PTGES3 Prostaglandin E synthase 3 (cytosolic)".
  6. ^ Freeman BC, Yamamoto KR (June 2002). "Disassembly of transcriptional regulatory complexes by molecular chaperones". Science. 296 (5576): 2232–2235. Bibcode:2002Sci...296.2232F. doi:10.1126/science.1073051. PMID 12077419. S2CID 8844179.

and 9 Related for: PTGES3 information

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PTGES3

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E synthase 3 (cytosolic) is an enzyme that in humans is encoded by the PTGES3 gene. The protein encoded by this gene is also known as p23 which functions...

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Aryl hydrocarbon receptor

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protein complex consisting of a dimer of Hsp90, prostaglandin E synthase 3 (PTGES3, p23) and a single molecule of the immunophilin-like AH receptor-interacting...

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Eicosanoid

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synthase pathway in which any one of three isozymes, PTGES, PTGES2, or PTGES3, convert PGH2 to PGE2 (subsequent products of this pathway include PGA2...

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Stress granule

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tract-binding protein 1 PTBP3 PTBP3 Polypyrimidine tract-binding protein 3 PTGES3 PTGES3 Prostaglandin E synthase 3 PTK2 FAK Protein Tyrosine Kinase 2 PUM1 Pumilio-1...

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P23

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boat P23, of the Armed Forces of Malta Papyrus 23, a biblical manuscript PTGES3, an enzyme Seligman Airport, in Yavapai County, Arizona, United States This...

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FKBP5

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mineralocorticoid-receptor complexes) along with the 90 kDa heat shock protein and PTGES3 (P23 protein). As an Hsp90-associated co-chaperone that regulates the responsiveness...

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Prostaglandin E synthase

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prostaglandin E synthase 3 (cytosolic) Identifiers Symbol PTGES3 Alt. symbols p23, TEBP, cPGES NCBI gene 10728 HGNC 16049 OMIM 607061 RefSeq NM_006601...

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SURF1

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assembly intermediate of cytochrome c oxidase complex (MITRAC complex). PTGES3, SLC25A5, COX6C, COX14, COA1 have all also been found to interact with SURF1...

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Cyclopentenone prostaglandins

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then converted to PGE2 by any one of three isozymes, PTGES, PTGES2, and PTGES3 or, alternatively, to PGD2 by either of two enzymes, a glutathione-independent...

Word Count : 3059

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