PIEZO1 information

PIEZO1 is a mechanosensitive ion channel protein that in humans is encoded by the gene PIEZO1. PIEZO1 and its close homolog PIEZO2 were cloned in 2010...

laureate of Armenian descent. He is known for his work in characterizing the PIEZO1, PIEZO2, and TRPM8 receptors that detect pressure, menthol, and temperature...

which is the first agonist developed for the mechanosensitive ion channel PIEZO1. This protein is involved in regulation of blood pressure and red blood...

from the Greek πιέζω, which means to squeeze or press, and may refer to: PIEZO1, a mechanosensitive ion protein Piezoelectric pickups for guitars and other...

2017). "Mechanical stretch triggers rapid epithelial cell division through Piezo1". Nature. 543 (7643): 118–121. Bibcode:2017Natur.543..118G. doi:10.1038/nature21407...

Thornton, Nicole M (19 September 2022). "Missense mutations in PIEZO1, encoding the Piezo1 mechanosensor protein, define the Er red blood cell antigens"...

lymphatic dysplasia of Fotiou or PIEZO1 disease, is an autosomal recessive genetic disease caused by mutations in the PIEZO1 gene. It results in lymphedema...

Hereditary xerocytosis is characterized by autosomal dominant mutations in PIEZO1, which encodes a cation channel whose mechanosensitive properties enable...

Jones, B.; Spring, F.A.; et al. (2022). "Missense mutations in PIEZO1, encoding the Piezo1 mechanosensor protein, define the Er red blood cell antigens"...

compound which acts as an agonist for the mechanosensitive ion channel PIEZO1, and is used in research into the function of touch perception. Yoda1 and...

deficiency, conditional knockout of Piezo1 increased bone formation. Notably, fecal ssRNA was identified as a natural Piezo1 ligand, and ssRNA-stimulated 5-HT...

eye". NBC News. Jan 1, 2010. Retrieved 3 January 2010. "Synergy between Piezo1 and Piezo2 channels confers high-strain mechanosensitivity to articular...

Baroreceptor mechanosensitivity is hypothesised to be linked to the expression of PIEZO1 and PIEZO2 on neurons in the petrosal and nodose ganglia. Baroreceptor action...

Marden-Walker syndrome and Arthrogryposis (Distal Arthrogryposis Type 5). PIEZO1 GRCh38: Ensembl release 89: ENSG00000154864 – Ensembl, May 2017 GRCm38:...

controversial It has been shown that odontoblast-neuron signal communication via Piezo1/TRPA1 channels and pannexin-1 in odontoblasts and P2X3 receptors in A-delta...

to monitor configurational changes of the mechanosensitive ion channel PIEZO1. Confocal microscopy Fluorescence Fluorescence microscope Fluorescence resonance...

domain channels and the recently cloned cation selective PIEZO family (PIEZO1 and PIEZO2). MSCs can be classified based on the type of ion to which they...

compound which acts as an agonist for the mechanosensitive ion channel PIEZO1, and is used in research into the function of touch perception. Yoda1 and...

Frederick; Guilak, Farshid; Liedtke, Wolfgang B. (2014-11-25). "Synergy between Piezo1 and Piezo2 channels confers high-strain mechanosensitivity to articular...

2017). "Mechanical stretch triggers rapid epithelial cell division through Piezo1". Nature. 543 (7643): 118–121. doi:10.1038/nature21407. ISSN 1476-4687....

Ganguly Lab recently discovered a novel regulatory module involving the Piezo1 mechanosensors in human T cells, driven by mechanical cues. They also provided...

Schmidt M., Earley T.J., Ranade S., Petrus M.J., Dubin A.E., Patapoutian A. Piezo1 and Piezo2 are essential components of distinct mechanically activated cation...

by crowding dependent activation of the stretch-activated cation channel Piezo1. Extrusion triggered by replicative stress or by cell competition requires...

magnetic field was employed to activate the mechanosensitive cation channel Piezo1. Results of this study show that remote, in vivo manipulation of behavior...

hereditary stomatocytosis, pseudohyperkalemia, and perinatal edema; 603528; PIEZO1 Dejerine–Sottas disease; 145900; PMP22 Dejerine–Sottas neuropathy; 145900;...