PARD3B information

PARD3B
Identifiers
Aliases	PARD3B, ALS2CR19, PAR3B, PAR3L, PAR3LC, PAR3beta, Par3Lb, par-3 family cell polarity regulator beta
External IDs	MGI: 1919301 HomoloGene: 35389 GeneCards: PARD3B
Gene location (Human)
Chr.	Chromosome 2 (human)
End	205,620,162 bp
Gene location (Mouse)
Chr.	Chromosome 1 (mouse)
End	62,681,443 bp
RNA expression pattern
	Top expressed in
	sural nerve; ; Achilles tendon; ; saphenous vein; ; right coronary artery; ; tibialis anterior muscle; ; germinal epithelium; ; subcutaneous adipose tissue; ; left coronary artery; ; synovial joint; ; spinal ganglia;
	Top expressed in
	crypt of lieberkuhn of small intestine; ; internal carotid artery; ; external carotid artery; ; sciatic nerve; ; renal corpuscle; ; ciliary body; ; iris; ; intestinal villus; ; carotid body; ; submandibular gland;
	More reference expression data
	n/a
Gene ontology
Molecular function	protein binding; phosphatidylinositol binding;
Cellular component	membrane; endomembrane system; bicellular tight junction; cell junction; nucleoplasm; nuclear body; protein-containing complex; cytoplasm; adherens junction; cell cortex; apical plasma membrane; apical junction complex;
Biological process	cell division; cell cycle; microtubule cytoskeleton organization; cell adhesion; protein localization; establishment of cell polarity; establishment or maintenance of epithelial cell apical/basal polarity; establishment of centrosome localization;
	Sources:Amigo / QuickGO
Orthologs
	117583
	72823
	ENSG00000116117
	ENSMUSG00000052062
	Q8TEW8
	Q9CSB4
	NM_001302769; NM_057177; NM_152526; NM_205863
	NM_001081050
	NP_001289698; NP_476518; NP_689739; NP_995585
	NP_001074519
	Wikidata
View/Edit Human	View/Edit Mouse

Partitioning defective 3 homolog B is a protein that in humans is encoded by the PARD3B gene.^[5]^[6]^[7]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000116117 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000052062 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Hadano S, Hand CK, Osuga H, Yanagisawa Y, Otomo A, Devon RS, Miyamoto N, Showguchi-Miyata J, Okada Y, Singaraja R, Figlewicz DA, Kwiatkowski T, Hosler BA, Sagie T, Skaug J, Nasir J, Brown RH Jr, Scherer SW, Rouleau GA, Hayden MR, Ikeda JE (Oct 2001). "A gene encoding a putative GTPase regulator is mutated in familial amyotrophic lateral sclerosis 2". Nat Genet. 29 (2): 166–73. doi:10.1038/ng1001-166. PMID 11586298. S2CID 52828189.
^ Kohjima M, Noda Y, Takeya R, Saito N, Takeuchi K, Sumimoto H (Dec 2002). "PAR3beta, a novel homologue of the cell polarity protein PAR3, localizes to tight junctions". Biochem Biophys Res Commun. 299 (4): 641–6. doi:10.1016/S0006-291X(02)02698-0. PMID 12459187.
^ "Entrez Gene: PARD3B par-3 partitioning defective 3 homolog B (C. elegans)".

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000116117 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000052062 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid11586298-5] Hadano S, Hand CK, Osuga H, Yanagisawa Y, Otomo A, Devon RS, Miyamoto N, Showguchi-Miyata J, Okada Y, Singaraja R, Figlewicz DA, Kwiatkowski T, Hosler BA, Sagie T, Skaug J, Nasir J, Brown RH Jr, Scherer SW, Rouleau GA, Hayden MR, Ikeda JE (Oct 2001). "A gene encoding a putative GTPase regulator is mutated in familial amyotrophic lateral sclerosis 2". Nat Genet. 29 (2): 166–73. doi:10.1038/ng1001-166. PMID 11586298. S2CID 52828189.

[pmid12459187-6] Kohjima M, Noda Y, Takeya R, Saito N, Takeuchi K, Sumimoto H (Dec 2002). "PAR3beta, a novel homologue of the cell polarity protein PAR3, localizes to tight junctions". Biochem Biophys Res Commun. 299 (4): 641–6. doi:10.1016/S0006-291X(02)02698-0. PMID 12459187.

[entrez-7] "Entrez Gene: PARD3B par-3 partitioning defective 3 homolog B (C. elegans)".

PARD3B information

and 3 Related for: PARD3B information

PARD3B

Chromosome 2

List of distinct cell types in the adult human body