Rare abdominal wall defect in which internal organs remain outside of the abdomen in a sac
Medical condition
Omphalocele
Infant before and after surgical treatment for exomphalos.
Specialty
Medical genetics
Symptoms
Visible organs
Usual onset
Congenital
Treatment
Surgical repair
Prognosis
varies- see below
Omphalocele or omphalocoele also called exomphalos, is a rare abdominal wall defect.[1] Beginning at the 6th week of development, rapid elongation of the gut and increased liver size reduces intra abdominal space, which pushes intestinal loops out of the abdominal cavity. Around 10th week, the intestine returns to the abdominal cavity and the process is completed by the 12th week.[2][3] Persistence of intestine or the presence of other abdominal viscera (e.g. stomach, liver) in the umbilical cord results in an omphalocele.
Omphalocele occurs in 1 in 4,000 births and is associated with a high rate of mortality (25%) and severe malformations, such as cardiac anomalies (50%), neural tube defect (40%), exstrophy of the bladder and Beckwith–Wiedemann syndrome. Approximately 15% of live-born infants with omphalocele have chromosomal abnormalities. About 30% of infants with an omphalocele have other congenital abnormalities.
^CDC (2019-12-05). "Facts about Omphalocele | CDC". Centers for Disease Control and Prevention. Retrieved 2020-12-20.
^Mann, Stephanie; Blinman, Thane A.; Douglas Wilson, R. (July 2008). "Prenatal and postnatal management of omphalocele". Prenatal Diagnosis. 28 (7): 626–632. doi:10.1002/pd.2008. ISSN 0197-3851. PMID 18634119. S2CID 206345744.
^Blaas, H.-G.; Eik-Nes, S. H.; Kiserud, T.; Hellevik, L. R. (1995). "Early development of the abdominal wall, stomach and heart from 7 to 12 weeks of gestation: a longitudinal ultrasound study". Ultrasound in Obstetrics & Gynecology. 6 (4): 240–249. doi:10.1046/j.1469-0705.1995.06040240.x. ISSN 1469-0705. PMID 8590186. S2CID 22318659.
Omphalocele or omphalocoele also called exomphalos, is a rare abdominal wall defect. Beginning at the 6th week of development, rapid elongation of the...
the diagnosis. Otherwise diagnosis occurs at birth. It differs from omphalocele in that there is no covering membrane over the intestines. Treatment...
Pediatric Surgery Case Reports. 35: 45–47. doi:10.1016/j.epsc.2018.05.016. "Omphalocele, exstrophy of the cloaca, imperforate anus, and spinal defects complex"...
mandibular prognathism), a narrow palate and crowding of the teeth. Omphalocele has been described in two patients with Apert syndrome by Herman T.E...
sparing technique for repair of congenital hernia into the cord and small omphalocele." Journal of Pediatric Surgery 52.1 (2017): 192-196. Herrine, Steven...
section. She died shortly after being born on September 26, 2006, due to omphalocele, a birth defect that caused her organs to grow outside her body. The...
(James Farrar), before discovering the baby has Edwards syndrome and omphalocele, which ultimately leads to her to terminating the pregnancy. In 2018...
body. Omphalocele occurs when some of the organs protrude through the muscles of the abdomen in the area surrounding the umbilical cord. Omphalocele can...
associated increased levels of acetylcholinesterase in the amnionic fluid), omphalocele, gastroschisis, multiple gestation (like twins or triplets), or an underestimation...
umbilical cord. If this persists after birth it is called an omphalocele. In omphalocele, there is a defect in the development of the anterior abdominal...
and involves a defect in the midline near to the umbilicus, and from omphalocele.[citation needed] Navels with the umbilical tip protruding past the umbilical...
a rare hereditary condition, which may include other defects such as omphalocele, visceromegaly, gigantism or neonatal hypoglycemia. The tongue may show...
and have a wide range of presentations. Diastasis recti, hernias, and omphalocele have all been described in conjunction with the pentalogy. Sternal defects...
hypoplastic left heart syndrome, other heart defects, esophageal atresia, omphalocele, intestinal malrotation, persistent cloaca, and other limb defects (most...
outlet right ventricle Non-cardiac malformations Pentalogy of Cantrell Omphalocele Anterior diaphragmatic hernia Cleft palate The diagnosis of ectopia cordis...
and four[citation needed]. Congenital heart defects, hydronephrosis, omphalocele and meningocele (spina bifida) are also common. Cystic hygromas occur...
Hudson (James Farrar); discovering that her baby has Edwards syndrome and omphalocele, which ultimately leads to her deciding to terminate her pregnancy; and...
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