In fields such as epidemiology, social sciences, psychology and statistics, an observational study draws inferences from a sample to a population where the independent variable is not under the control of the researcher because of ethical concerns or logistical constraints. One common observational study is about the possible effect of a treatment on subjects, where the assignment of subjects into a treated group versus a control group is outside the control of the investigator.[1][2] This is in contrast with experiments, such as randomized controlled trials, where each subject is randomly assigned to a treated group or a control group. Observational studies, for lacking an assignment mechanism, naturally present difficulties for inferential analysis.
^"Observational study". Archived from the original on 2016-04-27. Retrieved 2008-06-25.
^Porta M, ed. (2008). A Dictionary of Epidemiology (5th ed.). New York: Oxford University Press. ISBN 9780195314496.
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