Global InformationNS0 cell information
NS0 cells are a model cell line derived from the nonsecreting murine myeloma used in biomedical research and commercially in the production of therapeutic proteins.[1] The cell line is a cholesterol-dependent cell line that was generated from a subline of NSI/1 which produced only the light chain but no heavy chain.[2][3]
- ^ Barnes, LM; Bentley, CM; Dickson, AJ (February 2000). "Advances in animal cell recombinant protein production: GS-NS0 expression system". Cytotechnology. 32 (2): 109–23. doi:10.1023/A:1008170710003. PMC 3449689. PMID 19002973.
- ^ M. Barnes, Louise; Bentley, Catherine M.; Dickson, Alan J. (2000). "Advances in animal cell recombinant protein production: GS-NS0 expression system". Cytotechnology. 32 (2): 109–123. doi:10.1023/A:1008170710003. PMC 3449689. PMID 19002973.
- ^ Sato, JD; Cao, HT; Kayada, Y; Cabot, MC; Sato, GH; Okamoto, T; Welsh, CJ (December 1988). "Effects of proximate cholesterol precursors and steroid hormones on mouse myeloma growth in serum-free medium". In Vitro Cellular & Developmental Biology. 24 (12): 1223–8. doi:10.1007/bf02624194. PMID 3209588. S2CID 2470410.