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Names | |
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Preferred IUPAC name
(6S,7S,9E,12R)-12-[(2S,4E,6R,7R,9R)-7,9-Dihydroxy-4,6-dimethyldec-4-en-2-yl]-7,9-dimethyl-2-oxo-1-oxacyclododec-9-en-6-yl (2E,4E,6E,8E,10E,12S,13S,15S)-12,13,15-trihydroxy-4,6,10-trimethylhexadeca-2,4,6,8,10-pentaenoate | |
Identifiers | |
CAS Number
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3D model (JSmol)
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ChemSpider |
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MeSH | Mycolactone |
PubChem CID
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CompTox Dashboard (EPA)
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InChI
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SMILES
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Properties | |
Chemical formula
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C44H70O9 |
Molar mass | 743.021 |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
![]() ![]() ![]() Infobox references
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Mycolactone is a polyketide-derived macrolide produced and secreted by a group of very closely related pathogenic mycobacteria species including M. ulcerans, M. liflandii (an unofficial designation), M. pseudoshottsii, and some strains of M. marinum. These mycobacteria are collectively referred to as mycolactone-producing mycobacteria or MPM.[1][2]
In humans, mycolactone is the toxin responsible for Buruli ulcers, doing so by damaging tissues and inhibiting the immune response.[3]