Global InformationMulticolumn countercurrent solvent gradient purification information
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Multicolumn countercurrent solvent gradient purification (MCSGP) is a form of chromatography that is used to separate or purify biomolecules from complex mixtures. It was developed at the Swiss Federal Institute of Technology Zürich by Aumann and Morbidelli.[1] The process consists of two to six chromatographic columns which are connected to one another in such a way that as the mixture moves through the columns the compound is purified into several fractions.
- ^ Subramanian, Ganapathy (2007), Bioseparation and bioprocessing, Wiley-VCH, p. 235, ISBN 978-3-527-31585-7