Histopathology of signet ring cell carcinoma of urinary bladder on mucicarmine stain, coloring the mucin within tumor cells pink/red.
Mucicarmine stain is a staining procedure used for different purposes. In microbiology the stain aids in the identification of a variety of microorganisms based on whether or not the cell wall stains intensely red. Generally this is limited to microorganisms with a cell wall that is composed, at least in part, of a polysaccharide component. One of the organisms that is identified using this staining technique is Cryptococcus neoformans.[1]
Another use is in surgical pathology where it can identify mucin. This is helpful, for example, in determining if the cancer is a type that produces mucin.
Example would be to distinguish between high grade Mucoepidermoid Carcinoma of the parotid, which stains positive vs Squamous Cell Carcinoma of the parotid which does not.
^Lazcano, O (Jan 1993). "Combined histochemical stains in the differential diagnosis of Cryptococcus neoformans". Modern Pathology. 6 (1): 80–4. PMID 7678937.
Mucicarminestain is a staining procedure used for different purposes. In microbiology the stain aids in the identification of a variety of microorganisms...
forms are rarely seen. For identification in tissue, mucicarminestain provides specific staining of polysaccharide cell wall in C. neoformans. Cryptococcal...
Cryptococcosis of lung in patient with AIDS. Mucicarminestain. Histopathology of lung shows widened alveolar septum containing a few inflammatory cells...
organs, such as bronchi, lacrimal sac, and thyroid gland. Mucicarminestaining is one stain used by pathologist for detection. Presents as painless, slow-growing...
microscopy samples. However, they stain easily with the PAS staining method, which colours them magenta. In mucicarminestains, deep red mucin is found within...
histology, as Best's carmine to stain glycogen, mucicarmine to stain acidic mucopolysaccharides, and carmalum to stain cell nuclei. In these applications...
paraganglioma cells are argyrophilic, periodic acid Schiff negative, mucicarmine negative, and argentaffin negative.[citation needed] About 85% of paragangliomas...
p63 and calponin. Alcian blue will give a blue staining to the stromal matrix material. Mucicarmine will also highlight the stromal matrix (pink). There...
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