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Minimum information required in the annotation of models information


MIRIAM (Minimum Information Required In The Annotation of Models[1]) is a community-level effort to standardize the annotation and curation processes of quantitative models of biological systems.[2] It consists of a set of guidelines suitable for use with any structured format, allowing different groups to collaborate and share resulting models. Adherence to these guidelines also facilitates the sharing of software and service infrastructures built upon modeling activities.

The idea of "a set of good practices" including "some obligatory metadata" was first proposed by Nicolas Le Novère in October 2004 as part of a discussion to develop a common database of models in systems biology (which led to the creation of BioModels Database). These initial ideas were further refined at a meeting in Heidelberg, during ICSB 2004, with representatives from many other interested groups.

MIRIAM is a registered project of the MIBBI (minimum information for biological and biomedical investigations).[3]

  1. ^ The original article used the verb "requested", but this has evolved through community use into "required", and is in line with other Minimum Information (MI) standards available through the MIBBI portal
  2. ^ Novère, Nicolas Le; Finney, Andrew; Hucka, Michael; Bhalla, Upinder S; Campagne, Fabien; Collado-Vides, Julio; Crampin, Edmund J; Halstead, Matt; et al. (2005). "Minimum information requested in the annotation of biochemical models (MIRIAM)". Nature Biotechnology. 23 (12): 1509–15. doi:10.1038/nbt1156. hdl:11858/00-001M-0000-0010-853F-C. PMID 16333295.
  3. ^ http://www.mibbi.org/ Minimum Information for Biological and Biomedical Investigations[non-primary source needed]

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