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Michael Stratton information


Sir Michael Stratton
FRS FMedSci FRCPath
Born
Michael Rudolf Stratton

(1957-06-22) 22 June 1957 (age 66)[3]
EducationHaberdashers' Aske's Boys' School
Alma materUniversity of Oxford (BM BCh)
University of London (PhD)[9]
Known for
  • Cancer Genome Project
  • Discovery of BRCA2
  • Mutational signatures
Spouse
Judith Breuer
(m. 1981)
[3]
Awards
  • EMBO Member (2009)[1]
  • Knight Bachelor (2013)
Louis-Jeantet Prize for Medicine (2013) [2]
Scientific career
InstitutionsWellcome Trust Sanger Institute
Institute of Cancer Research
Guy's Hospital
University of Oxford[3]
ThesisRole of genetic alterations in the genesis of human soft tissue tumours and medulloblastoma (1990)
Doctoral studentsNazneen Rahman[4][5][6][7]
Ludmil Alexandrov[8]
Websitesanger.ac.uk/research/faculty/mstratton

Sir Michael Rudolf Stratton, FRS FMedSci FRCPath (born 22 June 1957) is a British clinical scientist and the third director of the Wellcome Trust Sanger Institute. He currently heads the Cancer Genome Project and is a leader of the International Cancer Genome Consortium.[10][11][12][13][14][15][16][17][18][19]

  1. ^ "EMBO welcomes 66 leading life scientists as members". biochemist.org. Archived from the original on 17 August 2014.
  2. ^ Louis-Jeantet Prize
  3. ^ a b c Anon (2015). "Stratton, Prof. Michael Rudolf". Who's Who (online Oxford University Press ed.). A & C Black. doi:10.1093/ww/9780199540884.013.U36509. (Subscription or UK public library membership required.)
  4. ^ Rahman, Nazneen (1999). Localisation and characterisation of the familial tumour gene, FWT1 (PhD thesis). University of London. EThOS uk.bl.ethos.314056.
  5. ^ "Royal Marsden: Professor Nazneen Rahman". Archived from the original on 2 February 2015.
  6. ^ Rahman, N; Arbour, L; Tonin, P; Renshaw, J; Pelletier, J; Baruchel, S; Pritchard-Jones, K; Stratton, M. R.; Narod, S. A. (1996). "Evidence for a familial Wilms' tumour gene (FWT1) on chromosome 17q12-q21". Nature Genetics. 13 (4): 461–3. doi:10.1038/ng0896-461. PMID 8696342. S2CID 19914321.
  7. ^ Rahman, N; Abidi, F; Ford, D; Arbour, L; Rapley, E; Tonin, P; Barton, D; Batcup, G; Berry, J; Cotter, F; Davison, V; Gerrard, M; Gray, E; Grundy, R; Hanafy, M; King, D; Lewis, I; Ridolfi Luethy, A; Madlensky, L; Mann, J; O'Meara, A; Oakhill, T; Skolnick, M; Strong, L; Stratton, M. R. (1998). "Confirmation of FWT1 as a Wilms' tumour susceptibility gene and phenotypic characteristics of Wilms' tumour attributable to FWT1". Human Genetics. 103 (5): 547–56. doi:10.1007/pl00008708. PMID 9860296. S2CID 7082835.
  8. ^ Alexandrov, Ludmil (2014). Signatures of mutational processes in human cancer (PDF). sanger.ac.uk (PhD thesis). University of Cambridge. OCLC 1064595163. EThOS uk.bl.ethos.708130.
  9. ^ Cite error: The named reference strattonphd was invoked but never defined (see the help page).
  10. ^ Michael Stratton's publications indexed by the Scopus bibliographic database. (subscription required)
  11. ^ Michael Stratton's publications in Google Scholar
  12. ^ International Cancer Genome Consortium; Hudson, T. J.; Anderson, W; Artez, A; Barker, A. D.; Bell, C; Bernabé, R. R.; Bhan, M. K.; Calvo, F; Eerola, I; Gerhard, D. S.; Guttmacher, A; Guyer, M; Hemsley, F. M.; Jennings, J. L.; Kerr, D; Klatt, P; Kolar, P; Kusada, J; Lane, D. P.; Laplace, F; Youyong, L; Nettekoven, G; Ozenberger, B; Peterson, J; Rao, T. S.; Remacle, J; Schafer, A. J.; Shibata, T; et al. (2010). "International network of cancer genome projects". Nature. 464 (7291): 993–8. Bibcode:2010Natur.464..993T. doi:10.1038/nature08987. PMC 2902243. PMID 20393554.
  13. ^ Mattison, J; Kool, J; Uren, A. G.; De Ridder, J; Wessels, L; Jonkers, J; Bignell, G. R.; Butler, A; Rust, A. G.; Brosch, M; Wilson, C. H.; Van Der Weyden, L; Largaespada, D. A.; Stratton, M. R.; Futreal, P. A.; Van Lohuizen, M; Berns, A; Collier, L. S.; Hubbard, T; Adams, D. J. (2010). "Novel candidate cancer genes identified by a large-scale cross-species comparative oncogenomics approach". Cancer Research. 70 (3): 883–95. doi:10.1158/0008-5472.CAN-09-1737. PMC 2880710. PMID 20103622.
  14. ^ Futreal, P. A.; Coin, L; Marshall, M; Down, T; Hubbard, T; Wooster, R; Rahman, N; Stratton, M. R. (2004). "A census of human cancer genes". Nature Reviews Cancer. 4 (3): 177–83. doi:10.1038/nrc1299. PMC 2665285. PMID 14993899.
  15. ^ Rapley, E. A.; Crockford, G. P.; Teare, D; Biggs, P; Seal, S; Barfoot, R; Edwards, S; Hamoudi, R; Heimdal, K; Fossâ, S. D.; Tucker, K; Donald, J; Collins, F; Friedlander, M; Hogg, D; Goss, P; Heidenreich, A; Ormiston, W; Daly, P. A.; Forman, D; Oliver, T. D.; Leahy, M; Huddart, R; Cooper, C. S.; Bodmer, J. G.; Easton, D. F.; Stratton, M. R.; Bishop, D. T. (2000). "Localization to Xq27 of a susceptibility gene for testicular germ-cell tumours". Nature Genetics. 24 (2): 197–200. doi:10.1038/72877. PMID 10655070. S2CID 9095109.
  16. ^ Hemminki, A.; Markie, D.; Tomlinson, I.; Avizienyte, E.; Roth, S.; Loukola, A.; Bignell, G.; Warren, W.; Aminoff, M.; Höglund, P.; Järvinen, H.; Kristo, P.; Pelin, K.; Ridanpää, M.; Salovaara, R.; Toro, T.; Bodmer, W.; Olschwang, S.; Olsen, A. S.; Stratton, M. R.; de la Chapelle, A.; Aaltonen, L. A. (1998). "A serine/threonine kinase gene defective in Peutz-Jeghers syndrome". Nature. 391 (6663): 184–7. Bibcode:1998Natur.391..184H. doi:10.1038/34432. PMID 9428765. S2CID 4400728.
  17. ^ Patterns of mutation in human cancer genomes – video of a seminar given by Stratton at the Royal Society.
  18. ^ Every human 'could get their own genome sequence' – Interview with Stratton on BBC's the Today Programme
  19. ^ "Feature: Professor Mike Stratton – how I got into cancer genetics 'Wellcome News' issue 66". 2011. Archived from the original on 20 March 2012.

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