Maclyn McCarty with Francis Crick and James D Watson
Born
(1911-06-09)June 9, 1911
South Bend, Indiana
Died
January 2, 2005(2005-01-02) (aged 93)
Known for
Role in the discovery that DNA is the carrier of genes
Awards
Eli Lilly and Company-Elanco Research Award 1946 Robert Koch Prize (Gold, 1981) Wolf Prize for Medicine (1990)
Maclyn McCarty (June 9, 1911 – January 2, 2005)[1] was an American geneticist, a research scientist described in 2005 as "the last surviving member of a Manhattan scientific team that overturned medical dogma in the 1940s and became the first to demonstrate that genes were made of DNA." He had worked at Rockefeller University "for more than 60 years."[1] 1994 marked 50 years since this work's release.[2]
McCarty devoted his life as a physician-scientist to studying infectious disease organisms, and was best known for his part in the monumental discovery that DNA, rather than protein, constituted the chemical nature of a gene. Uncovering the molecular secret of the gene in question — that for the capsular polysaccharide of pneumococcal bacteria — led the way to studying heredity not only through genetics but also through chemistry. The team responsible for this feat is known as the Avery–MacLeod–McCarty experiment. He died from congestive heart failure.
^ abLawrence K. Altman (January 6, 2005). "Maclyn McCarty Dies at 93; Pioneer in DNA Research". New York Times.
^Nadine Brozan (February 2, 1994). "CHRONICLE". New York Times.
MaclynMcCarty (June 9, 1911 – January 2, 2005) was an American geneticist, a research scientist described in 2005 as "the last surviving member of a Manhattan...
experiment (published in 1944 with his co-workers Colin MacLeod and MaclynMcCarty) that isolated DNA as the material of which genes and chromosomes are...
Thomas Francis Jr, Oswald T. Avery, Frederick Griffith, Colin MacLeod, MaclynMcCarty, Rebecca Lancefield, Wendell Meredith Stanley, René Dubos, Ashton Carter...
transform one serotype into another. Oswald Avery, Colin MacLeod, and MaclynMcCarty later showed that the transforming factor was deoxyribonucleic acid...
genetic information in bacteria. Oswald Avery, Colin Munro MacLeod, and MaclynMcCarty used an extract from a strain of pneumococcus that could cause pneumonia...
Colin MacLeod and MaclynMcCarty, identified DNA as the transforming principle, supporting Griffith's suggestion (Avery–MacLeod–McCarty experiment). Erwin...
The Career of MaclynMcCarty. PLoS Biol 3(10): e341 doi:10.1371/journal.pbio.0030341 "Selected Projects: The Architecture of Bruce McCarty"; Catalogue of...
researchers followed the trail. In 1944, Avery, Colin MacLeod, and MaclynMcCarty reported the transformation factor as DNA, widely doubted amid estimations...
gene, one enzyme" hypothesis. Oswald Avery, Colin Munro MacLeod, and MaclynMcCarty showed in 1944 that DNA holds the gene's information. In 1952, Rosalind...
heat-killed virulent pneumococci. In 1944, Oswald Avery, Colin MacLeod, and MaclynMcCarty demonstrated that the transforming factor in Griffith's experiment was...
politician, 55th United States Secretary of State (b. 1913) 2005 – MaclynMcCarty, American geneticist and physician (b. 1911) 2006 – Cecilia Muñoz-Palma...
45, American television writer (ER, L.A. Law), colorectal cancer. MaclynMcCarty, 93, American geneticist and DNA research pioneer, heart failure. Claude...
Health Institute MaclynMcCarty, youngest member of the research team responsible for the Avery–MacLeod–McCarty experiment Sherilyn S. McCoy, CEO of Avon...
was identified as being genetic by Oswald Avery, Colin MacLeod, and MaclynMcCarty. They isolated DNA from a virulent strain of S. pneumoniae and using...
which was identified as DNA in 1944 by Oswald Avery, Colin MacLeod, and MaclynMcCarty. Frederick Sanger developed a method for sequencing DNA in 1977, greatly...
from the smooth strain. Later on, Oswald Avery, Colin MacLeod, and MaclynMcCarty identified this transformational substance as DNA in 1944. Since DNA...
as a result of some experiments by Oswald Avery, Colin MacLeod, and MaclynMcCarty demonstrating that purified DNA could change one strain of bacteria...
American evolutionary biologist Phyllis McAlpine (1941–1998), Canadian human geneticist and gene mapper MaclynMcCarty (1911–2005), US co-discoverer that DNA...
in the Journal of Experimental Medicine by Avery, Colin MacLeod, and MaclynMcCarty of The Rockefeller Hospital. This identification departed from the prevailing...
into the pathogenic type. In 1944 Oswald Avery, Colin MacLeod, and MaclynMcCarty demonstrated that this 'transforming factor' was pure DNA . This was...
early years as a research scientist, MacLeod, with Oswald Avery and MaclynMcCarty, demonstrated DNA is the molecule responsible for bacterial transformation...
done by the microbiologist Oswald Avery and his Rockefeller colleagues MaclynMcCarty and Colin Macleod. Avery and his team had shown that nucleic acid could...
at Rockefeller in 1958. Lancefield was a long-time collaborator of MaclynMcCarty and a mentor of Emil Gotschlich, two recipients of the notable Lasker...
Global Information