Protein-coding gene in the species Homo sapiens
MXRA8 Identifiers Aliases MXRA8 , matrix remodeling associated 8, ASP3External IDs OMIM: 617293; MGI: 1922011; HomoloGene: 11500; GeneCards: MXRA8; OMA:MXRA8 - orthologs Gene location (Human) Chr. Chromosome 1 (human)[1] Band 1p36.33 Start 1,352,689 bp[1] End 1,361,777 bp[1]
Gene location (Mouse) Chr. Chromosome 4 (mouse)[2] Band 4 E2|4 87.58 cM Start 155,924,137 bp[2] End 155,928,545 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in stromal cell of endometrium tibial nerve decidua canal of the cervix body of uterus right coronary artery right ovary gallbladder left ovary ascending aorta
Top expressed in calvaria right lung ankle body of femur left lung right lung lobe stroma of bone marrow molar genital tubercle trachea
More reference expression data
BioGPS
Gene ontology Molecular function Cellular component
integral component of membrane
cell surface
extracellular exosome
membrane
endoplasmic reticulum lumen
nucleus
cytoplasm
plasma membrane
bicellular tight junction
cell junction
cell projection
ciliary membrane
Biological process
establishment of glial blood-brain barrier
post-translational protein modification
viral process
cell adhesion
Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez Ensembl UniProt RefSeq (mRNA) NM_032348 NM_001282582 NM_001282583 NM_001282584 NM_001282585
RefSeq (protein) NP_001269511 NP_001269512 NP_001269513 NP_001269514 NP_115724
Location (UCSC) Chr 1: 1.35 – 1.36 Mb Chr 4: 155.92 – 155.93 Mb PubMed search [3] [4]
Wikidata View/Edit Human View/Edit Mouse
Matrix remodeling associated 8 is a protein that in humans is encoded by the MXRA8 gene.[5]
MXRA8 protein is a receptor for multiple arthritogenic alphaviruses, including chikungunya, Ross River, Mayaro and O'nyong nyong viruses.[6]
^ a b c GRCh38: Ensembl release 89: ENSG00000162576 – Ensembl, May 2017
^ a b c GRCm38: Ensembl release 89: ENSMUSG00000029070 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine .
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine .
^
"Entrez Gene: Matrix remodeling associated 8". Retrieved 2018-10-22 .
^ Zhang R, Kim AS, Fox JM, et al. (May 2018). "Mxra8 is a receptor for multiple arthritogenic alphaviruses". Nature . 557 (7706): 570–574. Bibcode:2018Natur.557..570Z. doi:10.1038/s41586-018-0121-3. PMC 5970976 . PMID 29769725.