MMP21 information

MMP21
Identifiers
Aliases	MMP21, MMP-21, HTX7, matrix metallopeptidase 21
External IDs	OMIM: 608416; MGI: 2664387; HomoloGene: 17519; GeneCards: MMP21; OMA:MMP21 - orthologs
Gene location (Human)
Chr.	Chromosome 10 (human)
End	125,775,821 bp
Gene location (Mouse)
Chr.	Chromosome 7 (mouse)
End	133,281,790 bp
RNA expression pattern
	Top expressed in
	gonad; ; corpus epididymis; ; testicle; ; left ovary; ; right ovary; ; body of pancreas; ; minor salivary glands; ; ectocervix; ; right auricle; ; right uterine tube;
	Top expressed in
	embryo; ; blastocyst; ; right kidney;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	metallopeptidase activity; metal ion binding; zinc ion binding; metalloendopeptidase activity; peptidase activity; hydrolase activity;
Cellular component	extracellular region; extracellular matrix;
Biological process	hematopoietic progenitor cell differentiation; proteolysis; coronary vasculature development; determination of left/right symmetry; determination of heart left/right asymmetry; extracellular matrix organization; collagen catabolic process;
	Sources:Amigo / QuickGO
Orthologs
	118856
	214766
	ENSG00000154485
	ENSMUSG00000030981
	Q8N119
	Q8K3F2
	NM_147191
	NM_152944; NM_001320216
	NP_671724
	NP_001307145; NP_694423
	Wikidata
View/Edit Human	View/Edit Mouse

Matrix metalloproteinase-21 (MMP-21) is an enzyme that in humans is encoded by the MMP21 gene.^[5]^[6]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000154485 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000030981 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Marchenko GN, Strongin AY (Mar 2001). "MMP-28, a new human matrix metalloproteinase with an unusual cysteine-switch sequence is widely expressed in tumors". Gene. 265 (1–2): 87–93. doi:10.1016/S0378-1119(01)00360-2. PMID 11255011.
^ Cite error: The named reference entrez was invoked but never defined (see the help page).

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