Class of enzyme which catalyzes elimination reactions
This article is about the group of enzymes. For the language, see Lyase language.
In biochemistry, a lyase is an enzyme that catalyzes the breaking (an elimination reaction) of various chemical bonds by means other than hydrolysis (a substitution reaction) and oxidation, often forming a new double bond or a new ring structure.[1] The reverse reaction is also possible (called a Michael reaction). For example, an enzyme that catalyzed this reaction would be a lyase:
ATP → cAMP + PPi
Lyases differ from other enzymes in that they require only one substrate for the reaction in one direction, but two substrates for the reverse reaction.
In biochemistry, a lyase is an enzyme that catalyzes the breaking (an elimination reaction) of various chemical bonds by means other than hydrolysis (a...
The enzyme methylisocitrate lyase (EC 4.1.3.30) catalyzes the chemical reaction (2S,3R)-3-hydroxybutane-1,2,3-tricarboxylate ⇌ {\displaystyle \rightleftharpoons...
Adenylosuccinate lyase (or adenylosuccinase) is an enzyme that in humans is encoded by the ADSL gene. Adenylosuccinate lyase converts adenylosuccinate...
The enzyme heparin lyase (EC 4.2.2.7) catalyzes the following process: Eliminative cleavage of polysaccharides containing (1→4)-linked D-glucuronate or...
The enzyme carboxymethyloxysuccinate lyase (EC 4.2.99.12) catalyzes the chemical reaction carboxymethyloxysuccinate ⇌ {\displaystyle \rightleftharpoons...
family of lyases, specifically amidine lyases. The systematic name of this enzyme class is [peptide]-(2S)-2-hydroxyglycine peptidyl-amide-lyase (glyoxylate-forming)...
Pectate lyase (EC 4.2.2.2) is an enzyme involved in the maceration and soft rotting of plant tissue. Pectate lyase is responsible for the eliminative cleavage...
Farnesylcysteine lyase (EC 1.8.3.6, FC lyase, FCLY) is an enzyme with systematic name S-(2E,6E)-farnesyl-L-cysteine oxidase. This enzyme catalyses the...
Hydroxynitrile lyase may refer to: hydroxynitrilase, an enzyme (S)-hydroxynitrile lyase, an enzyme This set index page lists enzyme articles associated...
Pectin lyase is a polysaccharide enzyme with a complex structure that is present in plant cell walls. It has a significant role in pectin degradation...
of lyases, specifically the oxo-acid-lyases, which cleave carbon-carbon bonds. The systematic name of this enzyme class is chorismate pyruvate-lyase...
belongs to the family of lyases, specifically amidine lyases. The systematic name of this enzyme class is (S)-ureidoglycolate urea-lyase (glyoxylate-forming)...
(steroid 17α-monooxygenase, 17α-hydroxylase, 17-alpha-hydroxylase, 17,20-lyase, 17,20-desmolase) is an enzyme of the hydroxylase type that in humans is...
ATP citrate synthase (also ATP citrate lyase (ACLY)) is an enzyme that in animals represents an important step in fatty acid biosynthesis. By converting...
The enzyme (R)-mandelonitrile lyase (EC 4.1.2.10, (R)-HNL, (R)-oxynitrilase, (R)-hydroxynitrile lyase) catalyzes the chemical reaction mandelonitrile...
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