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LiMAx test
Figure 1: Methacetin is metabolized by the hepatic cytochrome P450 1A2 specific to acetaminophen and 13C-formaldehyde, which is then converted in several fast enzymatic steps to 13CO2
Purpose
liver function test
The LiMAx test (maximum liver function capacity) is a dynamic liver function test based on the metabolism of 13C-methacetin by the liver-specific cytochrome P450 1A2 system. The test can be carried out at bedside displaying actual liver function at the point of measurement (Point-of-care testing).
The LiMAxtest (maximum liver function capacity) is a dynamic liver function test based on the metabolism of 13C-methacetin by the liver-specific cytochrome...
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