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Lectican information


Lecticans, also known as hyalectans, are a family of proteoglycans (a type protein that is attached to chains of negatively charged polysaccharides) that are components of the extracellular matrix. There are four members of the lectican family: aggrecan, brevican, neurocan, and versican. Lecticans interact with hyaluronic acid and tenascin-R to form a ternary complex.[1]

  1. ^ Yamaguchi Y (2000). "Lecticans: organizers of the brain extracellular matrix". Cell. Mol. Life Sci. 57 (2): 276–89. doi:10.1007/PL00000690. PMC 11146776. PMID 10766023. S2CID 15744515.

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Lectican

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Lecticans, also known as hyalectans, are a family of proteoglycans (a type protein that is attached to chains of negatively charged polysaccharides) that...

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Versican

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recognition of its versatile modular structure. Versican belongs to the lectican protein family, with aggrecan (abundant in cartilage), brevican and neurocan...

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Aggrecan

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that in humans is encoded by the ACAN gene. This gene is a member of the lectican (chondroitin sulfate proteoglycan) family. The encoded protein is an integral...

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Brevican

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that in humans is encoded by the BCAN gene. Brevican is a member of the lectican protein family. Brevican is localised to the surface of neurons in the...

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Neurocan

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that in humans is encoded by the NCAN gene. Neurocan is a member of the lectican / chondroitin sulfate proteoglycan protein families and consists of neurocan...

Word Count : 1039
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