LSM3 information

LSM3
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	3JCR
Identifiers
Aliases	LSM3, SMX4, USS2, YLR438C, LSM3 homolog, U6 small nuclear RNA and mRNA degradation associated
External IDs	OMIM: 607283 MGI: 1914928 HomoloGene: 6548 GeneCards: LSM3
Gene location (Human)
Chr.	Chromosome 3 (human)
End	14,201,122 bp
Gene location (Mouse)
Chr.	Chromosome 6 (mouse)
End	91,499,607 bp
RNA expression pattern
	Top expressed in
	biceps brachii; ; thoracic diaphragm; ; right ventricle; ; oral cavity; ; triceps brachii muscle; ; trabecular bone; ; body of tongue; ; corpus epididymis; ; seminal vesicula; ; synovial joint;
	Top expressed in
	blastocyst; ; yolk sac; ; thymus; ; placenta; ; bone marrow; ; neural tube; ; morula; ; spermatocyte; ; white adipose tissue; ; ileum;
	More reference expression data
	n/a
Gene ontology
Molecular function	protein binding; RNA binding;
Cellular component	U6 snRNP; cytosol; Lsm1-7-Pat1 complex; catalytic step 2 spliceosome; P-body; U4/U6 x U5 tri-snRNP complex; spliceosomal complex; precatalytic spliceosome; nucleus; nucleoplasm; U2-type precatalytic spliceosome; Lsm2-8 complex;
Biological process	mRNA processing; P-body assembly; exonucleolytic catabolism of deadenylated mRNA; RNA splicing; mRNA splicing, via spliceosome; nuclear-transcribed mRNA catabolic process;
	Sources:Amigo / QuickGO
Orthologs
	27258
	67678
	ENSG00000170860
	ENSMUSG00000034192
	P62310
	P62311
	NM_014463
	NM_026309
	NP_055278
	NP_080585
	Wikidata
View/Edit Human	View/Edit Mouse

U6 snRNA-associated Sm-like protein LSm3 is a protein that in humans is encoded by the LSM3 gene.^[5]^[6]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000170860 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000034192 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Salgado-Garrido J, Bragado-Nilsson E, Kandels-Lewis S, Séraphin B (Jun 1999). "Sm and Sm-like proteins assemble in two related complexes of deep evolutionary origin". The EMBO Journal. 18 (12): 3451–62. doi:10.1093/emboj/18.12.3451. PMC 1171424. PMID 10369684.
^ "Entrez Gene: LSM3 LSM3 homolog, U6 small nuclear RNA associated (S. cerevisiae)".

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