dentate gyrus of hippocampal formation granule cell
hippocampus proper
primary visual cortex
temporal lobe
amygdala
superior frontal gyrus
subdivision of hippocampus
subiculum
Region I of hippocampus proper
More reference expression data
BioGPS
More reference expression data
Gene ontology
Molecular function
signaling receptor binding
protein binding
Cellular component
extracellular region
cell junction
synapse
extracellular space
membrane
synaptic cleft
glutamatergic synapse
Biological process
positive regulation of cell growth
cell population proliferation
neuron projection development
positive regulation of synaptic transmission
protein homooligomerization
nervous system development
axon guidance
neurotransmitter receptor localization to postsynaptic specialization membrane
Sources:Amigo / QuickGO
Orthologs
Species
Human
Mouse
Entrez
9211
56839
Ensembl
ENSG00000108231
ENSMUSG00000067242
UniProt
O95970
Q9JIA1
RefSeq (mRNA)
NM_001308275 NM_001308276 NM_005097
NM_020278
RefSeq (protein)
NP_001295204 NP_001295205 NP_005088
NP_064674
Location (UCSC)
Chr 10: 93.76 – 93.81 Mb
Chr 19: 38.25 – 38.3 Mb
PubMed search
[3]
[4]
Wikidata
View/Edit Human
View/Edit Mouse
Leucine-rich, glioma inactivated 1, also known as LGI1, is a protein which in humans is encoded by the LGI1 gene.[5] It may be a metastasis suppressor.
^ abcGRCh38: Ensembl release 89: ENSG00000108231 – Ensembl, May 2017
^ abcGRCm38: Ensembl release 89: ENSMUSG00000067242 – Ensembl, May 2017
^"Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^"Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^Cite error: The named reference entrez was invoked but never defined (see the help page).
Leucine-rich, glioma inactivated 1, also known as LGI1, is a protein which in humans is encoded by the LGI1 gene. It may be a metastasis suppressor. The leucine-rich...
that form a complex with VGKC called leucine-rich glioma-inactivated 1 (LGI1) and contactin-associated protein-like 2 (CASPR-2). Each of these antibodies...
phonologic processing in familial lateral temporal lobe epilepsy due to a new LGI1 mutation". Epilepsia. 46 (1): 118–23. doi:10.1111/j.0013-9580.2005.26304...
myasthenia gravis, and glycine receptors or potassium channel-associated proteins LGI1, CASPR2 and Contactin-2 in CNS diseases. She demonstrated that transfer of...
Grzeschik KH, Derst C, Brodtkorb E, de Vos R, Steinlein OK (May 2002). "The LGI1 gene involved in lateral temporal lobe epilepsy belongs to a new subfamily...
generalized seizures This disorder is caused by mutations in either the LGI1 gene or the RELN gene. These mutations are inherited in an autosomal dominant...
Global Information
