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Kunitz STI protease inhibitor information


Trypsin and protease inhibitor
Structure of a Kunitz-type trypsin inhibitor.[1]
Identifiers
SymbolKunitz_legume
PfamPF00197
InterProIPR002160
PROSITEPDOC00255
SCOP21tie / SCOPe / SUPFAM
Available protein structures:
Pfam  structures / ECOD  
PDBRCSB PDB; PDBe; PDBj
PDBsumstructure summary
PDB1ava​, 1avu​, 1ba7​ , 1eyl​, 1fmz​, 1fn0​, 1r8n​, 1tie​, 1wba​, 1wbc​, 1xg6​, 2bea​, 2beb​, 2esu​, 2et2​, 2iwt​, 2wbc​, 4wbc

Kunitz soybean trypsin inhibitor is a type of protein contained in legume seeds which functions as a protease inhibitor.[2] Kunitz-type Soybean Trypsin Inhibitors are usually specific for either trypsin or chymotrypsin. They are thought to protect seeds against consumption by animal predators.

  1. ^ PDB: 1tie​; Onesti S, Brick P, Blow DM (January 1991). "Crystal structure of a Kunitz-type trypsin inhibitor from Erythrina caffra seeds". J. Mol. Biol. 217 (1): 153–76. doi:10.1016/0022-2836(91)90618-G. PMID 1988676. S2CID 46210915.
  2. ^ Rawlings ND, Tolle DP, Barrett AJ (March 2004). "Evolutionary families of peptidase inhibitors". Biochem. J. 378 (Pt 3): 705–16. doi:10.1042/BJ20031825. PMC 1224039. PMID 14705960.

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