Articular cartilage, most notably that which is found in the knee joint, is generally characterized by very low friction, high wear resistance, and poor regenerative qualities. It is responsible for much of the compressive resistance and load bearing qualities of the knee joint and, without it, walking is painful to impossible. Osteoarthritis is a common condition of cartilage failure that can lead to limited range of motion, bone damage and invariably, pain. Due to a combination of acute stress and chronic fatigue, osteoarthritis directly manifests itself in a wearing away of the articular surface and, in extreme cases, bone can be exposed in the joint. Some additional examples of cartilage failure mechanisms include cellular matrix linkage rupture, chondrocyte protein synthesis inhibition, and chondrocyte apoptosis. There are several different repair options available for cartilage damage or failure.
"Maci" or autologous cultured chondrocytes on porcine collagen membrane, is a treatment to correct cartilage defects in the knee. This treatment has been approved by the Food and Drug Administration in 2016 for adult treatment only.[1]
^"FDA approves first autologous cellularized scaffold for the repair of cartilage defects of the knee". US Food and Drug Administration. 13 December 2016. Retrieved 28 November 2017.
and 26 Related for: Knee cartilage replacement therapy information
Articular cartilage, most notably that which is found in the knee joint, is generally characterized by very low friction, high wear resistance, and poor...
Meniscal cartilagereplacementtherapy is surgical replacement of the meniscus of the knee as a treatment for where the meniscus is so damaged that it...
Kneereplacement, also known as knee arthroplasty, is a surgical procedure to replace the weight-bearing surfaces of the knee joint to relieve pain and...
detachment: The cartilage in the knee is frequently damaged but can be partially repaired through kneecartilagereplacementtherapy. Often when athletes...
arthritis, or reactive arthritis. The knee is one of the joints most commonly affected by osteoarthritis. Cartilage in the knee may begin to break down after...
osteoarthritic articular cartilage from human knee joints. With special reference to unicompartmental replacement and osteotomy of the knee". The Journal of Bone...
surgery Hand surgery Hemilaminectomy Image-guided surgery Kneecartilagereplacementtherapy Laminectomy Laparoscopic surgery Lithotomy Lithotriptor Lobotomy...
the fibrocartilage strips in the knee called menisci. When doctors and patients refer to "torn cartilage" in the knee, they actually may be referring to...
cartilage has become a dominant area of research. The growing number of people suffering from osteoarthritis and the potential of some gene therapy approaches...
damage, or delaying the need for joint replacement (kneereplacement) surgery. Though the different articular cartilage repair procedures differ in the technologies...
improvement in hip function. Hip replacement is usually considered only after other therapies, such as physical therapy and pain medications, have failed...
Joint replacement is considered as a treatment when severe joint pain or dysfunction is not alleviated by less-invasive therapies. Joint replacement surgery...
Captique (Dermal filler), for facial wrinkles. Carticel (Kneecartilagereplacementtherapy), for knee pain. Cerdelga (Eliglustat), for type 1 gaucher disease...
treatments for knee pain include physical therapy exercises, pain-reducing drugs such as ibuprofen, joint stretching, kneereplacement surgery, and weight...
the opposite direction compared to the knee. The benefit to the patient is that they have a functioning knee joint to which a prosthetic can be fitted...
damaged or dead bone tissue and cartilage in a process called bone remodeling. While OCD may affect any joint, the knee tends to be the most commonly affected...
the knee, and level of activity following treatment. Not repairing tears to the ACL can sometimes cause damage to the cartilage inside the knee because...
standard total kneereplacement surgery, the unicompartmental kneereplacement, in which only one weight-bearing surface of an arthritic knee is replaced...
placebo (fake) surgery or other treatments (such as exercise therapy). During an average knee arthroscopy, a small fiberoptic camera (the arthroscope) is...
joint lining and cartilage which eventually results in erosion of two opposing bones. RA often affects joints in the fingers, wrists, knees and elbows, is...
used following various types of reconstructive joint surgery such as kneereplacement and ACL reconstruction. Its mechanisms of action for aiding joint recovery...
total kneereplacement. Wikimedia Commons has media related to Medial meniscus. meniscus tear of meniscus cartilage unhappy triad meniscal cartilage replacement...
joint replacement (kneereplacement) surgery. ACI procedures aim to provide complete hyaline repair tissues for articular cartilage repair. Over the last...
muscles surrounding the knee, a KO can prevent flexion, extension, or instability of the knee. If the ligaments or cartilage of the knee are affected, a KO...
Global Information