KDM4C information

KDM4C
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	2XDP, 2XML, 4XDO, 4XDP, 5FJK, 5FJH
Identifiers
Aliases	KDM4C, GASC1, JHDM3C, JMJD2C, TDRD14C, bA146B14.1, lysine demethylase 4C
External IDs	OMIM: 605469; MGI: 1924054; HomoloGene: 41004; GeneCards: KDM4C; OMA:KDM4C - orthologs
Gene location (Human)
Chr.	Chromosome 9 (human)
End	7,175,648 bp
Gene location (Mouse)
Chr.	Chromosome 4 (mouse)
End	74,324,097 bp
RNA expression pattern
	Top expressed in
	bone marrow cells; ; thymus; ; Achilles tendon; ; sural nerve; ; corpus callosum; ; body of pancreas; ; monocyte; ; rectum; ; cerebellar vermis; ; stomach;
	Top expressed in
	saccule; ; otic placode; ; lacrimal gland; ; retinal pigment epithelium; ; interventricular septum; ; pineal gland; ; superior cervical ganglion; ; olfactory epithelium; ; iris; ; salivary gland;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	oxidoreductase activity; histone H3-methyl-lysine-9 demethylase activity; dioxygenase activity; metal ion binding; chromatin binding; enzyme binding; histone demethylase activity; androgen receptor binding; zinc ion binding; histone H3-methyl-lysine-36 demethylase activity; DNA-binding transcription repressor activity, RNA polymerase II-specific; methylated histone binding;
Cellular component	nucleus; nucleoplasm; pericentric heterochromatin; histone methyltransferase complex;
Biological process	regulation of transcription by RNA polymerase II; regulation of transcription, DNA-templated; transcription, DNA-templated; positive regulation of cell population proliferation; blastocyst formation; regulation of gene expression; positive regulation of gene expression; histone H3-K9 demethylation; positive regulation of neuron differentiation; negative regulation of histone H3-K9 trimethylation; regulation of stem cell population maintenance; regulation of stem cell differentiation; histone H3-K36 demethylation; chromatin organization; negative regulation of transcription by RNA polymerase II; chromatin remodeling; stem cell population maintenance;
	Sources:Amigo / QuickGO
Orthologs
	23081
	76804
	ENSG00000107077
	ENSMUSG00000028397
	Q9H3R0
	Q8VCD7
NM_001146694; NM_001146695; NM_001146696; NM_001304339; NM_001304340;
	NM_001304341; NM_015061; NM_001353997; NM_001353998; NM_001353999; NM_001354000; NM_001354001
	NM_001172095; NM_144787; NM_001356561
NP_001140167; NP_001140168; NP_001291268; NP_001291269; NP_001291270;
	NP_055876; NP_001340926; NP_001340927; NP_001340928; NP_001340929; NP_001340930
	NP_001165566; NP_659036; NP_001343490
	Wikidata
View/Edit Human	View/Edit Mouse

Lysine-specific demethylase 4C is an enzyme that in humans is encoded by the KDM4C gene.^[5]^[6]^[7]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000107077 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000028397 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Nagase T, Ishikawa K, Suyama M, Kikuno R, Miyajima N, Tanaka A, Kotani H, Nomura N, Ohara O (Oct 1998). "Prediction of the coding sequences of unidentified human genes. XI. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro". DNA Research. 5 (5): 277–86. doi:10.1093/dnares/5.5.277. PMID 9872452.
^ Katoh M, Katoh M (Jun 2004). "Identification and characterization of JMJD2 family genes in silico". International Journal of Oncology. 24 (6): 1623–8. doi:10.3892/ijo.25.3.759. PMID 15138608.
^ "Entrez Gene: JMJD2C jumonji domain containing 2C".

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000107077 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000028397 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid9872452-5] Nagase T, Ishikawa K, Suyama M, Kikuno R, Miyajima N, Tanaka A, Kotani H, Nomura N, Ohara O (Oct 1998). "Prediction of the coding sequences of unidentified human genes. XI. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro". DNA Research. 5 (5): 277–86. doi:10.1093/dnares/5.5.277. PMID 9872452.

[pmid15138608-6] Katoh M, Katoh M (Jun 2004). "Identification and characterization of JMJD2 family genes in silico". International Journal of Oncology. 24 (6): 1623–8. doi:10.3892/ijo.25.3.759. PMID 15138608.

[entrez-7] "Entrez Gene: JMJD2C jumonji domain containing 2C".

KDM4C information

and 2 Related for: KDM4C information

KDM4C

Demethylase