KCNF1 information

KCNF1
Identifiers
Aliases	KCNF1, IK8, KCNF, KV5.1, kH1, potassium voltage-gated channel modifier subfamily F member 1
External IDs	OMIM: 603787; MGI: 2687399; HomoloGene: 124236; GeneCards: KCNF1; OMA:KCNF1 - orthologs
Gene location (Human)
Chr.	Chromosome 2 (human)
End	10,914,225 bp
Gene location (Mouse)
Chr.	Chromosome 12 (mouse)
End	17,226,889 bp
RNA expression pattern
	Top expressed in
	prefrontal cortex; ; putamen; ; nucleus accumbens; ; right frontal lobe; ; caudate nucleus; ; cingulate gyrus; ; anterior cingulate cortex; ; dorsolateral prefrontal cortex; ; Brodmann area 9; ; orbitofrontal cortex;
	Top expressed in
	temporal lobe; ; prefrontal cortex; ; amygdala; ; piriform cortex; ; olfactory bulb; ; superior frontal gyrus; ; supraoptic nucleus; ; primary visual cortex; ; nucleus accumbens; ; primary motor cortex;
	More reference expression data
	n/a
Gene ontology
Molecular function	ion channel activity; potassium channel activity; voltage-gated ion channel activity; voltage-gated potassium channel activity;
Cellular component	integral component of membrane; voltage-gated potassium channel complex; plasma membrane; membrane;
Biological process	potassium ion transport; regulation of ion transmembrane transport; protein homooligomerization; ion transport; transmembrane transport; potassium ion transmembrane transport;
	Sources:Amigo / QuickGO
Orthologs
	3754
	382571
	ENSG00000162975
	ENSMUSG00000051726
	Q9H3M0
	Q7TSH7
	NM_002236
	NM_201531
	NP_002227
	NP_963289
	Wikidata
View/Edit Human	View/Edit Mouse

Potassium voltage-gated channel subfamily F member 1 is a protein that in humans is encoded by the KCNF1 gene.^[5]^[6] The protein encoded by this gene is a voltage-gated potassium channel subunit.^[6]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000162975 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000051726 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Su K, Kyaw H, Fan P, Zeng Z, Shell BK, Carter KC, Li Y (Feb 1998). "Isolation, characterization, and mapping of two human potassium channels". Biochem Biophys Res Commun. 241 (3): 675–81. doi:10.1006/bbrc.1997.7830. PMID 9434767.
^ ^a ^b Gutman GA, Chandy KG, Grissmer S, Lazdunski M, McKinnon D, Pardo LA, Robertson GA, Rudy B, Sanguinetti MC, Stuhmer W, Wang X (Dec 2005). "International Union of Pharmacology. LIII. Nomenclature and molecular relationships of voltage-gated potassium channels". Pharmacol Rev. 57 (4): 473–508. doi:10.1124/pr.57.4.10. PMID 16382104. S2CID 219195192.

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000162975 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000051726 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid9434767-5] Su K, Kyaw H, Fan P, Zeng Z, Shell BK, Carter KC, Li Y (Feb 1998). "Isolation, characterization, and mapping of two human potassium channels". Biochem Biophys Res Commun. 241 (3): 675–81. doi:10.1006/bbrc.1997.7830. PMID 9434767.

[pmid16382104-6] Gutman GA, Chandy KG, Grissmer S, Lazdunski M, McKinnon D, Pardo LA, Robertson GA, Rudy B, Sanguinetti MC, Stuhmer W, Wang X (Dec 2005). "International Union of Pharmacology. LIII. Nomenclature and molecular relationships of voltage-gated potassium channels". Pharmacol Rev. 57 (4): 473–508. doi:10.1124/pr.57.4.10. PMID 16382104. S2CID 219195192.

KCNF1 information

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