Juxtaglomerular cell tumor (JCT, JGCT, also reninoma) is an extremely rare kidney tumour of the juxtaglomerular cells, with fewer than 100 cases reported in literature. This tumor typically secretes renin, hence the former name of reninoma. It often causes severe hypertension that is difficult to control, in adults and children, although among causes of secondary hypertension it is rare. It develops most commonly in young adults, but can be diagnosed much later in life. It is generally considered benign, but its malignant potential is uncertain.[1]
^Capovilla M, Couturier J, Molinié V, Amsellem-Ouazana D, Priollet P, Baumert H, Bruneval P, Vieillefond A (March 2008). "Loss of chromosomes 9 and 11 may be recurrent chromosome imbalances in juxtaglomerular cell tumors". Hum. Pathol. 39 (3): 459–62. doi:10.1016/j.humpath.2007.08.010. PMID 18261631.
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Juxtaglomerularcells (JG cells), also known as juxtaglomerular granular cells are cells in the kidney that synthesize, store, and secrete the enzyme renin...
Juxtaglomerularcelltumor (JCT, JGCT, also reninoma) is an extremely rare kidney tumour of the juxtaglomerularcells, with fewer than 100 cases reported...
The juxtaglomerular apparatus is named because it is next to (juxta-) the glomerulus. The juxtaglomerular apparatus consists of three types of cells: the...
microvessels of the kidney from specialized cells of the juxtaglomerular apparatus—the juxtaglomerularcells, in response to three stimuli: A decrease in...
spindle cell carcinoma Mixed epithelial stromal tumorTumors that are considered benign include angiomyolipoma, oncocytoma, reninoma (juxtaglomerularcell tumor)...
United Kingdom J. C. Tenorio Enterprises, a Marianan conglomerate Juxtaglomerularcelltumor, in renal medicine Jordan curve theorem, in mathematics JCT FC...
extent the concentration of ACTH. Sensors of blood pressure in the juxtaglomerular apparatus of the kidneys release the enzyme renin into the blood, which...
pressure by stimulating renin release in macula densa and juxtaglomerular apparatus cells via GPR91. Therapies targeting succinate to reduce cardiovascular...
in specialized smooth muscle within the afferent arteriole of the juxtaglomerular apparatus, which secretes renin in response to osmotic and pressure...
low perfusion pressure that is detected by the juxtaglomerular apparatus (via the macula densa cells, which act as baroreceptors; located on the afferent...
renin-angiotensin II-aldosterone system, a system composed of baroreceptors and juxtaglomerularcells. Changes in the homeostasis of the human body, such as osmolality...
Instead of measuring it directly in the blood flowing past the juxtaglomerularcells, these cells respond to the sodium concentration in the renal tubular fluid...
release to the juxtaglomerularcells nearby. The juxtaglomerularcells in the afferent arteriole constrict, and juxtaglomerularcells in both the afferent...
renin–angiotensin–aldosterone system (RAAS). Renin production in the juxtaglomerularcells of the kidney is induced by decreased arterial blood pressure, decreased...
rate and cause a decrease in renin released from the granular cells of the juxtaglomerular apparatus in the kidney decreasing sodium reabsorption and returning...
affected nephrons. This decrease in blood flow is recognized by the juxtaglomerular (JG) cells and promotes the cleavage of prorenin into renin. Each kidney...
Houot A.M., Ménard J. and Corvol P. Renin biosynthesis by human tumoraljuxtaglomerularcells: evidence for a renin precursor. J. Clin. Invest. 73 : 1144–1155...
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