For other people named John Cornforth, see John Cornforth (disambiguation).
Sir
John Cornforth
AC CBE FRS FAA
Cornforth in 1975
Born
John Warcup Cornforth Jr.
(1917-09-07)7 September 1917
Sydney, New South Wales, Australia
Died
8 December 2013(2013-12-08) (aged 96)
Sussex, England
Nationality
Australian
Citizenship
Australian British
Alma mater
University of Sydney (BSc)
St Catherine's College, Oxford (DPhil)
Known for
Stereochemistry of enzyme-catalysed reactions Cholesterol total synthesis Cornforth reagent Cornforth rearrangement
Spouse
Rita Harradence
Awards
Corday–Morgan Medal (1953)
FRS (1953)[1][2]
Davy Medal (1968)
Ernest Guenther Award (1969)
Nobel Prize in Chemistry (1975)
Royal Medal (1976)
Copley Medal (1982)
Scientific career
Fields
Organic chemistry
Institutions
University of Oxford
University of Warwick
University of Sussex
Thesis
Synthesis of analogues of steroid hormones(1941)
Doctoral advisor
Robert Robinson
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Sir John Warcup Cornforth Jr.,[3]AC, CBE, FRS, FAA (7 September 1917 – 8 December 2013) was an Australian–British chemist who won the Nobel Prize in Chemistry in 1975 for his work on the stereochemistry of enzyme-catalysed reactions,[4][5] becoming the only Nobel laureate born in New South Wales.[2][6][7]
Cornforth investigated enzymes that catalyse changes in organic compounds, the substrates, by taking the place of hydrogen atoms in a substrate's chains and rings. In his syntheses and descriptions of the structure of various terpenes, olefins, and steroids, Cornforth determined specifically which cluster of hydrogen atoms in a substrate were replaced by an enzyme to effect a given change in the substrate, allowing him to detail the biosynthesis of cholesterol.[8] For this work, he won a share of the Nobel Prize in Chemistry in 1975, alongside co-recipient Vladimir Prelog, and was knighted in 1977.[9]
^Cite error: The named reference royal was invoked but never defined (see the help page).
^ abBattersby, Sir Alan R.; Young, Douglas W. (2015). "Sir John Warcup Cornforth AC CBE. 7 September 1917 – 8 December 2013". Biographical Memoirs of Fellows of the Royal Society. 62: 19–57. doi:10.1098/rsbm.2015.0016. ISSN 0080-4606.
^"John Cornforth". NNDB. Retrieved 1 July 2017.
^Hanson, Jim (2014). "John Cornforth (1917–2013) Nobel-prizewinning chemist who tracked how enzymes build cholesterol". Nature. 506 (7486): 35. Bibcode:2014Natur.506...35H. doi:10.1038/506035a. PMID 24499912.
^"Sir John Cornforth". Encyclopædia Britannica. 2012.
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after the Australian-British chemist Sir John Warcup Cornforth (b. 1917) who introduced it in 1962. The Cornforth reagent is a strong oxidizing agent which...
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ring exchange places. It was first reported in 1949, and is named for JohnCornforth. The reaction is used in the synthesis of amino acids, where the corresponding...
scientific achievement. The research group of Robert Robinson with JohnCornforth (Oxford University) published their synthesis in 1951 and that of Robert...
Autobiography". www.nobelprize.org. Archived from the original on 9 June 2010. "JohnCornforth - Autobiography". www.nobelprize.org. Archived from the original on...
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Former Diplomat and first-ever black head of an Oxford college Sir JohnCornforth, Nobel Laureate in Chemistry David Li GBM, GBS, OBE, JP, Chairman and...
Colvin, A Biographical Dictionary of British Architects, 3rd ed., 1995. JohnCornforth, Early Georgian Interiors (Paul Mellon Centre), 2005. James Stevens...
Rita Harriet Harradence, Lady Cornforth (16 September 1915 − 6 November 2012) was an Australian biochemist who pioneered the synthesis of penicillamine...
Roger Cornforth (19 January 1919 – 19 March 1976) was Captain of North Sydney Boys High School in 1935. His brother was Sir JohnCornforth who shared the...
tetramine and tetrathiomolybdate. Penicillamine was first synthesized by JohnCornforth under supervision of Robert Robinson. Penicillamine has been used in...
warfare activities in Germany 1923–1945". In: Geissler, Erhard and Moon, John Ellis van Courtland, eds., Biological warfare from the Middle Ages to 1945...
Eighteenth-Century Inventories of Great English Houses. A Tribute to JohnCornforth. Cambridge: John Adamson, 2006, pp. 169–205 ISBN 978-0-9524322-5-8 OCLC 78044620...
brains. As a class, we did not like brains." The architectural historian JohnCornforth suggests that the purchase was funded by the Prince himself, "out of...
Nobel Peace Prize twice. Also the Nobel Prize in Physics was awarded to John Bardeen twice, as was the Nobel Prize in Chemistry to Frederick Sanger and...
Great English Houses. A Tribute to John Cornforth. Cambridge: John Adamson. ISBN 978-0-9524322-5-8. Robinson, John Martin, The English Country Estate, 1988...
rare, expensive, and dangerous chemical. In the UK in the early 1950s, JohnCornforth and Kenneth Callow at the National Institute for Medical Research collaborated...
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