Isometamidium chloride is a triazene trypanocidal agent used in veterinary medicine.[1][2]
It consists of a single ethidium bromide like subunit linked to a fragment of the diminazene molecule.[citation needed]
^Whitelaw DD, Bell IR, Holmes PH, Moloo SK, Hirumi H, Urquhart GM, Murray M (June 1986). "Isometamidium chloride prophylaxis against Trypanosoma congolense challenge and the development of immune responses in Boran cattle". The Veterinary Record. 118 (26): 722–6. doi:10.1136/vr.118.26.722. PMID 3739193. S2CID 39168151.
^Peregrine AS, Ogunyemi O, Whitelaw DD, Holmes PH, Moloo SK, Hirumi H, et al. (April 1988). "Factors influencing the duration of isometamidium chloride (Samorin) prophylaxis against experimental challenge with metacyclic forms of Trypanosoma congolense". Veterinary Parasitology. 28 (1–2): 53–64. doi:10.1016/0304-4017(88)90018-0. PMID 3388736.
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Isometamidiumchloride is a triazene trypanocidal agent used in veterinary medicine. It consists of a single ethidium bromide like subunit linked to a...
makes this treatment impractical in some areas, where the related isometamidiumchloride is used instead. Despite its reputation as a mutagen, tests have...
diminazene aceturate, homidium (homidium bromide and homidium chloride), isometamidiumchloride, melarsomine, quinapyramine, and suramin. They are all highly...
the primary reason for human infectivity. Suramin is recommended. Isometamidiumchloride is ineffective. Trypanosoma evansi trypanocide resistance is widespread...
for the tested trypanocides, diminazene aceturate, isometamidiumchloride, and homidium chloride. "Trypanosoma congolense". American Association of Veterinary...
ELISA and fluorescent antibody testing. Chemical treatment with isometamidiumchloride has been effective. There is a vaccine against C. salmositica which...