Global InformationIsoeugenol synthase information
| Isoeugenol synthase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 1.1.1.319 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| |||||||||
Isoeugenol synthase (EC 1.1.1.319, IGS1, t-anol/isoeugenol synthase 1) is an enzyme with systematic name eugenol:NADP+ oxidoreductase (coniferyl acetate reducing).[1][2][3] This enzyme catalyses the following chemical reaction.[4]
- isoeugenol + acetate + NADP+ coniferyl acetate + NADPH + H+
The enzyme acts in the reverse direction.
Dexter et al., 2007 finds that the substrate is coniferyl acetate.[5]
- ^ Koeduka T, Fridman E, Gang DR, Vassão DG, Jackson BL, Kish CM, Orlova I, Spassova SM, Lewis NG, Noel JP, Baiga TJ, Dudareva N, Pichersky E (June 2006). "Eugenol and isoeugenol, characteristic aromatic constituents of spices, are biosynthesized via reduction of a coniferyl alcohol ester". Proceedings of the National Academy of Sciences of the United States of America. 103 (26): 10128–33. doi:10.1073/pnas.0603732103. PMC 1502517. PMID 16782809.
- ^ Koeduka T, Louie GV, Orlova I, Kish CM, Ibdah M, Wilkerson CG, Bowman ME, Baiga TJ, Noel JP, Dudareva N, Pichersky E (May 2008). "The multiple phenylpropene synthases in both Clarkia breweri and Petunia hybrida represent two distinct protein lineages". The Plant Journal. 54 (3): 362–74. doi:10.1111/j.1365-313X.2008.03412.x. PMC 2741023. PMID 18208524.
- ^ Koeduka T, Baiga TJ, Noel JP, Pichersky E (January 2009). "Biosynthesis of t-anethole in anise: characterization of t-anol/isoeugenol synthase and an O-methyltransferase specific for a C7-C8 propenyl side chain". Plant Physiology. 149 (1): 384–94. doi:10.1104/pp.108.128066. PMC 2613694. PMID 18987218.
- ^ Gupta AK, Schauvinhold I, Pichersky E, Schiestl FP (December 2014). "Eugenol synthase genes in floral scent variation in Gymnadenia species" (PDF). Functional & Integrative Genomics. 14 (4): 779–88. doi:10.1007/s10142-014-0397-9. hdl:20.500.11850/91540. PMID 25239559. S2CID 17207240.
- ^
- Vogt, Thomas (2010). "Phenylpropanoid Biosynthesis". Molecular Plant. 3 (1): 2–20. doi:10.1093/mp/ssp106. PMID 20035037. S2CID 39503278.
- This review cites this research.
- Dexter, Richard; Qualley, Anthony; Kish, Christine M.; Ma, Choong Je; Koeduka, Takao; Nagegowda, Dinesh A.; Dudareva, Natalia; Pichersky, Eran; Clark, David (2006-12-07). "Characterization of a petunia acetyltransferase involved in the biosynthesis of the floral volatile isoeugenol". The Plant Journal. 49 (2): 265–275. doi:10.1111/j.1365-313x.2006.02954.x. hdl:2027.42/74478. PMID 17241449. S2CID 6714361.