Immune dysregulation is any proposed or confirmed breakdown or maladaptive change in molecular control of immune system processes. For example, dysregulation is a component in the pathogenesis of autoimmune diseases and some cancers. Immune system dysfunction, as seen in IPEX syndrome leads to immune dysfunction, polyendocrinopathy, enteropathy, X-linked (IPEX). IPEX typically presents during the first few months of life with diabetes mellitus, intractable diarrhea, failure to thrive, eczema, and hemolytic anemia. unrestrained or unregulated immune response.[1]
^Wildin RS, Smyk-Pearson S, Filipovich AH (August 2002). "Clinical and molecular features of the immunodysregulation, polyendocrinopathy, enteropathy, X linked (IPEX) syndrome". J Med Genet. 39 (8): 537–45. doi:10.1136/jmg.39.8.537. PMID 12161590.
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Immunedysregulation is any proposed or confirmed breakdown or maladaptive change in molecular control of immune system processes. For example, dysregulation...
destruction by the immune system or failure of the myelin-producing cells. Proposed causes for this include immunedysregulation, genetics, and environmental...
Major depression is often associated or correlated with immune function dysregulation, and the two are thought to share similar physiological pathways...
Epigenetics of autoimmune disorders List of autoimmune diseases Immunedysregulation "Autoimmune diseases". Office on Women's Health. U.S. Department...
Possible causes such as aflatoxin poisoning, oxidative stress, immunedysregulation, and altered gut microbiota have been suggested. Treatment can help...
TREX1, SAMHD1 or IFIH1 mutations Spondyloenchondro-dysplasia with immunedysregulation (ACP5 mutation) STING-associated vasculopathy with onset in infancy...
pathology and inflammation in CVID that is a part of the general immunedysregulation affecting patients with CVID. The most common upper gastrointestinal...
potentially leading to life-threatening lung disease characterized by immunedysregulation. RSV has evolved numerous strategies to evade the host's antiviral...
serotonin signaling and inflammation. A 2015 review proposed that immunedysregulation, gastrointestinal inflammation, autonomic nervous system malfunction...
most prominent being Autoimmune polyendocrine syndrome type 1 and immunedysregulation polyendocrinopathy enteropathy X-linked (IPEX) syndrome. Clinical...
Levy J, Bernstein L, Silber N (December 2014). "Celiac disease: an immunedysregulation syndrome". Current Problems in Pediatric and Adolescent Health Care...
antigen-presenting cells and terminate the immune response leads to uncontrolled proliferation and activation of the immune system with release of excessive cytokines...
1258/0956462054308440. PMID 16004624. S2CID 21471620. Regauer, S (2005). "Immunedysregulation in lichen sclerosus". European Journal of Cell Biology. 84 (2–3):...
haploinsufficiency. Since LRBA loss results in a loss of CTLA4 protein, the immunedysregulation syndrome of LRBA deficient patients can be attributed to the secondary...
dysregulation of neurohormones. Under stimulation, norepinephrine is released from the sympathetic nerve terminals in organs, and the target immune cells...
Levy J, Bernstein L, Silber N (December 2014). "Celiac disease: an immunedysregulation syndrome". Current Problems in Pediatric and Adolescent Health Care...
deficiency and immunedysregulation, first described in 2012. The name is an acronym of "PLCG2-associated antibody deficiency and immunedysregulation". It is...
Insulin autoimmune syndrome (IAS), a rare cause of reversible autoimmune hypoglycemia also known as Hirata's disease, was first described by Hirata in...
517–528. doi:10.1038/nrgastro.2016.107. PMC 5005185. PMID 27435372. immunedysregulation, GI inflammation, malfunction of the ANS, genetic and metabolic activity...
Auxiliary T cells are a key element of HIV-1 infection. Several signs of immunedysregulation such as polyclonal B cell initialization, previous cell-mediated...
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