Transmission electron micrograph of human coronavirus 229E
Virus classification
(unranked):
Virus
Realm:
Riboviria
Kingdom:
Orthornavirae
Phylum:
Pisuviricota
Class:
Pisoniviricetes
Order:
Nidovirales
Family:
Coronaviridae
Genus:
Alphacoronavirus
Subgenus:
Duvinacovirus
Species:
Human coronavirus 229E
Human coronavirus 229E (HCoV-229E) is a species of coronavirus which infects humans and bats.[1] It is an enveloped, positive-sense, single-stranded RNA virus which enters its host cell by binding to the APN receptor.[2] Along with Human coronavirus OC43 (a member of the Betacoronavirus genus), it is one of the viruses responsible for the common cold.[3][4] HCoV-229E is a member of the genus Alphacoronavirus and subgenus Duvinacovirus.[5][6]
^Lim, Yvonne Xinyi; Ng, Yan Ling; Tam, James P.; Liu, Ding Xiang (2016-07-25). "Human Coronaviruses: A Review of Virus–Host Interactions". Diseases. 4 (3): 26. doi:10.3390/diseases4030026. ISSN 2079-9721. PMC 5456285. PMID 28933406. See Table 1.
^Fehr AR, Perlman S (2015). "Coronaviruses: An Overview of Their Replication and Pathogenesis". In Maier HJ, Bickerton E, Britton P (eds.). Coronaviruses. Methods in Molecular Biology. Vol. 1282. Springer. pp. 1–23. doi:10.1007/978-1-4939-2438-7_1. ISBN 978-1-4939-2438-7. PMC 4369385. PMID 25720466. See Table 1.
^Lau, S. K.; Lee, P.; Tsang, A. K.; Yip, C. C.; Tse, H.; Lee, R. A.; So, L. Y.; Lau, Y. L.; Chan, K. H.; Woo, P. C.; Yuen, K. Y. (2011). "Molecular epidemiology of human coronavirus OC43 reveals evolution of different genotypes over time and recent emergence of a novel genotype due to natural recombination". Journal of Virology. 85 (21): 11325–11337. doi:10.1128/JVI.05512-11. PMC 3194943. PMID 21849456.
^Gaunt, E. R.; Hardie, A.; Claas, E. C.; Simmonds, P.; Templeton, K. E. (2010). "Epidemiology and clinical presentations of the four human coronaviruses 229E, HKU1, NL63, and OC43 detected over 3 years using a novel multiplex real-time PCR method". Journal of Clinical Microbiology. 48 (8): 2940–2947. doi:10.1128/JCM.00636-10. PMC 2916580. PMID 20554810.
^"Virus Taxonomy: 2018 Release". International Committee on Taxonomy of Viruses (ICTV). October 2018. Retrieved 13 January 2019.
^Woo, Patrick C. Y.; Huang, Yi; Lau, Susanna K. P.; Yuen, Kwok-Yung (2010-08-24). "Coronavirus Genomics and Bioinformatics Analysis". Viruses. 2 (8): 1804–1820. doi:10.3390/v2081803. ISSN 1999-4915. PMC 3185738. PMID 21994708. Figure 2. Phylogenetic analysis of RNA-dependent RNA polymerases (Pol) of coronaviruses with complete genome sequences available. The tree was constructed by the neighbor-joining method and rooted using Breda virus polyprotein.
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morphological appearance. Humancoronavirus229E and humancoronavirus OC43 continued to be studied in subsequent decades. The coronavirus strain B814 was lost...
Humancoronavirus HKU1 (HCoV-HKU1) is a species of coronavirus in humans and animals. It causes an upper respiratory disease with symptoms of the common...
Humancoronavirus OC43 (HCoV-OC43) is a member of the species Betacoronavirus 1, which infects humans and cattle. The infecting coronavirus is an enveloped...
Humancoronavirus NL63 (HCoV-NL63) is a species of coronavirus, specifically a Setracovirus from among the Alphacoronavirus genus. It was identified in...
merged with Rat coronavirus (discovered in 1970) and Puffinosis coronavirus (discovered in 1982) as Murine coronavirus in 2009. 229E and OC43 were collectively...
Coronavirus diseases are caused by viruses in the coronavirus subfamily, a group of related RNA viruses that cause diseases in mammals and birds. In humans...
cells. It is a receptor for humancoronavirus229E, feline coronavirus serotype II (FCoV-II), TGEV, PEDV, canine coronavirus genotype II (CCoV-II) as well...
Thomas; Holmes, Kathryn V. (June 1992). "Human aminopeptidase N is a receptor for humancoronavirus229E". Nature. 357 (6377): 420–422. Bibcode:1992Natur...
but is clearly distinct from the other families infecting humans. Viruses known to infect humans that have not been associated with disease: the family Anelloviridae...
that is currently known as Severe acute respiratory syndrome-related coronavirus which, per the 2021 mandate from the ICTV, will also receive a binomial...
Characterization of a Novel Alpaca Respiratory Coronavirus Most Closely Related to the HumanCoronavirus229E". Viruses. 4 (12): 3689–3700. doi:10.3390/v4123689...
cannot be measured by classical plaque assays. These viruses include humancoronavirus229E and OC43. Susceptible cells are inoculated with serial logarithmic...
human coronaviruses (HCoV) known to be endemic: 229E, OC43, NL63, and HKU1. In May 2013, the Coronavirus Study Group of the International Committee on Taxonomy...
World Health Organization (WHO). "Coronavirus disease (COVID-19) Pandemic". World Health Organization (WHO). "Coronavirus Disease 2019 (COVID-19)". Centers...
geocola Humancoronavirus229EHumancoronavirus HKU1 Humancoronavirus NL63 Human immunodeficiency virus 1 Human immunodeficiency virus 2 Human mastadenovirus...
Vero/MSPL cells SADS TGEV PRCV Feline coronavirus Canine coronavirus. A recent recombinant CCoV-HuPn-2018 including a human case HKU5 SARS-S chimera HKU5 and...
HumanCoronavirus-Erasmus Medical Center (HCoV-EMC), the virus's genetic makeup, and closest relatives (including SARS). In May 2013, the Coronavirus...
Potassium Channel (F-Kch) Family 1.A.89 The HumanCoronavirus229E Viroporin (229E Viroporin) Family 1.A.90 The Human Metapneumovirus (HMPV) Viroporin (HMPV-Viroporin)...
Middle East respiratory syndrome (MERS), Humancoronavirus OC43, Humancoronavirus229E and the coronavirus disease. These coronaviruses have all evolved...
Global Information
