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Heterocyclic amine information


Niacin, essential to many types of life, is an example of a heterocyclic amine.

Heterocyclic amines, also sometimes referred to as HCAs, are chemical compounds containing at least one heterocyclic ring, which by definition has atoms of at least two different elements, as well as at least one amine (nitrogen-containing) group. Typically it is a nitrogen atom of an amine group that also makes the ring heterocyclic (e.g., pyridine), though compounds exist in which this is not the case (e.g., the drug Zileuton). The biological functions of heterocyclic amines vary, including vitamins and carcinogens. Carcinogenic heterocyclic amines are created by high temperature cooking of meat and smoking of plant matter like tobacco. Some well known heterocyclic amines are niacin (vitamin B3), nicotine (psychoactive alkaloid and recreational drug), and the nucleobases that encode genetic information in DNA.

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Heterocyclic amine

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Heterocyclic amines, also sometimes referred to as HCAs, are chemical compounds containing at least one heterocyclic ring, which by definition has atoms...

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Heterocyclic amine formation in meat

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Heterocyclic amines are a group of chemical compounds, many of which can be formed during cooking. They are found in meats that are cooked to the "well...

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Heterocyclic compound

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related to heterocyclic compounds. Wikiquote has quotations related to Heterocyclic compound. Hantzsch-Widman nomenclature, IUPAC Heterocyclic amines in cooked...

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Piperidine

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formula (CH2)5NH. This heterocyclic amine consists of a six-membered ring containing five methylene bridges (–CH2–) and one amine bridge (–NH–). It is a...

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Grilling

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poultry, and fish at high temperatures can lead to the formation of heterocyclic amines, benzopyrenes, and polycyclic aromatic hydrocarbons, which are carcinogens...

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Carcinogen

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carcinogens include polycyclic aromatic hydrocarbons (PAHs), heterocyclic aromatic amines, and mycotoxins. Activation-independent carcinogens, or "direct-acting"...

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C12H10N2

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linked by a N=N double bond Harmane, a heterocyclic amine found in a variety of foods 9-Me-BC, a heterocyclic amine of the beta-carboline family This set...

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Hot dog

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and "all-natural" franks. Hot dogs have relatively low carcinogenic heterocyclic amine (HCA) levels compared to other types of ready-to-eat meat products...

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Harmane

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Harmane (harman) is a heterocyclic amine found in a variety of foods including coffee, sauces, and cooked meat. It is also present in tobacco smoke. Harmane...

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Cooking

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since 1990 indicate that cooking meat at high temperature creates heterocyclic amines (HCAs), which are thought to increase cancer risk in humans. Researchers...

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Meat floss

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processing temperatures of meat floss and increased formation of heterocyclic aromatic amines (HAAs) within the meat. Up to seven different HAAs were found...

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Cancer

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044. PMID 17484871. Zheng W, Lee SA (2009). "Well-done meat intake, heterocyclic amine exposure, and cancer risk". Nutrition and Cancer. 61 (4): 437–46....

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Dibenzoylmethane

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"Inhibitory Effect of Dibenzoylmethane on Mutagenicity of Food-Derived Heterocyclic Amine Mutagens". Phytomedicine. 10 (6–7): 575–582. doi:10.1078/094471103322331575...

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Meat

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per 50g/d increment of processed meat. Cooking muscle meat creates heterocyclic amines (HCAs), which are thought to increase cancer risk in humans. Researchers...

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Marination

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muscle proteins at high temperature can lead to the formation of heterocyclic amines (HCAs). Food portal Barbecue sauce – flavoring sauce used as a marinade...

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HCA

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school in Pagadian City, Philippines Heterocyclic amine, a type of chemical compound containing at least one heterocyclic ring Hexachloroacetone, an organic...

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Mutagen

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aflatoxins which may be present in contaminated peanuts and corn; heterocyclic amines generated in meat when cooked at high temperature; PAHs in charred...

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Reuterin

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(November 2016). "Acrolein contributes strongly to antimicrobial and heterocyclic amine transformation activities of reuterin". Scientific Reports. 6 (1):...

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Creatine

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temperatures (above 148 °C), the resulting reaction produces carcinogenic heterocyclic amines (HCAs). Such a reaction happens when grilling or pan-frying meat...

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Umpolung

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has been formed between two carbons that are normally electrophiles. N-heterocyclic carbenes are similar to cyanide in reactivity. Like cyanide, they have...

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Red meat

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N-nitroso compounds, polycyclic aromatic hydrocarbons (PAHs), and heterocyclic amines (HCAs). Cooking meat with "high-temperature methods, such as pan...

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Acrolein

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(2016-11-07). "Acrolein contributes strongly to antimicrobial and heterocyclic amine transformation activities of reuterin". Scientific Reports. 6 (1):...

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Cytosine

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RNA). It is a pyrimidine derivative, with a heterocyclic aromatic ring and two substituents attached (an amine group at position 4 and a keto group at position...

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