HepaRG cell line is a human hepatic in vitro line used in liver biology research and for assessing liver pathology, hepatotoxicity, and drug-induced injury. The HepaRG model is considered a surrogate for Primary Human Hepatocytes, which are the most pertinent model to reproduce the human liver functioning as they express 99% of the same genes.
In contrast to the historic hepatic line HepG2, HepaRG cells preserved various liver-specific functions, including the expression of CYP enzymes and transporters, the formation of bile canaliculi, and, the ability to be applied in 2D and 3D configuration.
HepaRG cell line is a human hepatic in vitro line used in liver biology research and for assessing liver pathology, hepatotoxicity, and drug-induced injury...
2015). "Metronidazole reduces the expression of cytochrome P450 enzymes in HepaRG cells and cryopreserved human hepatocytes". Xenobiotica; the Fate of Foreign...
plated cultures of primary hepatocytes or hepatocyte-like cell lines (HepG2, HepaRG) can be used to study and quantify metabolism of chemicals. These ADME process...
types: primary tupaia, or human hepatocytes (PHH), and differentiated HepaRG (dHepaRG). It is from these models that HBV replication was observed via transcription...
Pyrrolizidine Alkaloids and Structure-Dependent Induction of Apoptosis in HepaRG Cells". Oxidative Medicine and Cellular Longevity. 2021: e8822304. doi:10...
2015). "Metronidazole reduces the expression of cytochrome P450 enzymes in HepaRG cells and cryopreserved human hepatocytes". Xenobiotica; the Fate of Foreign...
(NTRC) show local exhaust ventilation and High Efficiency Particulate Air (HEPA) filtration to be effective mitigation to theoretically filter 99.97% of...
difficulties in getting blood vessels and lab-made tissues to function cohesively. HepaLife is developing a bioartificial liver device intended for the treatment...
Anthropology and Applied Human Science, 23: 205–213, 2004 Springer, W. E., Nevins, R.G., Feyerherm, A.M., Michaels, K.B., Effect of floor surface temperature on...
liquid soap through sealed dispensers, paper towels or hand dryers with HEPA filter or fabric towel rolls and signage with proper hand washing steps....
protocols are typically used, especially in wastewater reuse applications. HEPA filter Portable water purification Sanitation Sanitation Standard Operating...
still no agreement on their relevance: HEPACAM: A cross-reactivity between HepaCam (GlialCam) and EBNA1 has been reported as of 2022 on 25% of MS cases Anti-kir4...