Human Y chromosome DNA grouping indicating common ancestry
Haplogroup CF
Possible time of origin
75,000-70,000 BP
Possible place of origin
Possibly Africa[1]
Ancestor
CT
Descendants
C, F
Defining mutations
P143
Haplogroup CF, also known as CF-P143 and CT(xDE), is a human Y-chromosome DNA haplogroup. This paternal lineage is defined by the SNP P143. The clade's existence and distribution are inferred from the fact that haplogroups descended from CF include most human male lineages in Eurasia, Oceania and The Americas.
CF is an immediate descendant of the Haplogroup CT (CT-M168), and is the sibling of Haplogroup DE (DE-YAP). It is the immediate ancestor of both Haplogroup C and Haplogroup F.[2]
There are, as yet, no confirmed cases of living individuals or human remains belonging to the basal, undivergent haplogroup CF*. In the year 2017, C-M217 (C2) & C-M130 were reported among males belonging to the Shan peoples, who are concentrated in central-east Burma (as well as neighboring parts of China, Laos and Thailand).[3] However, the researchers concerned (Brunelli et al.) did not rule out all other subclades of CF, such as haplogroup F, in these particular cases.[citation needed] (In haplogroup F2 has previously been identified in the same geographical region.[4])
^Haber, Marc; Jones, Abigail L; Connell, Bruce A; Arciero, Elena; Yang, Huanming; Thomas, Mark G; Xue, Yali; Tyler-Smith, Chris (2019). "A Rare Deep-Rooting D0 African Y-Chromosomal Haplogroup and Its Implications for the Expansion of Modern Humans Out of Africa". Genetics. 212 (4): 1421–1428. doi:10.1534/genetics.119.302368. PMC 6707464. PMID 31196864.
^Underhill PA, Kivisild T (2007). "Use of Y chromosome and mitochondrial DNA population structure in tracing human migrations". Annu. Rev. Genet. 41: 539–64. doi:10.1146/annurev.genet.41.110306.130407. PMID 18076332.
^Brunelli, Andrea (July 24, 2017). "Y chromosomal evidence on the origin of northern Thai people". PLOS ONE. 12 (7): e0181935. Bibcode:2017PLoSO..1281935B. doi:10.1371/journal.pone.0181935. PMC 5524406. PMID 28742125.
^Black, M.L.; Wise, C.A.; Wang, W.; Bittles, A.H. (June 2006). "Combining Genetics and Population History in the Study of Ethnic Diversity in the People's Republic of China". Human Biology. 78 (3): 277–293. doi:10.1353/hub.2006.0041. PMID 17216801. S2CID 42002729.
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