HOXA2 information

HOXA2
Identifiers
Aliases	HOXA2, HOX1K, MCOHI, homeobox A2
External IDs	OMIM: 604685; MGI: 96174; HomoloGene: 4901; GeneCards: HOXA2; OMA:HOXA2 - orthologs
Gene location (Human)
Chr.	Chromosome 7 (human)
End	27,102,686 bp
Gene location (Mouse)
Chr.	Chromosome 6 (mouse)
End	52,141,811 bp
RNA expression pattern
	Top expressed in
	mucosa of transverse colon; ; Descending thoracic aorta; ; C1 segment; ; gastric mucosa; ; left uterine tube; ; ascending aorta; ; muscle layer of sigmoid colon; ; body of uterus; ; tibial arteries; ; rectum;
	Top expressed in
	neuromere; ; rhombomere; ; tail of embryo; ; thoracic diaphragm; ; main bronchus; ; tongue; ; genital tubercle; ; female urethra; ; hair; ; ureter;
	More reference expression data
	n/a
Gene ontology
Molecular function	DNA binding; sequence-specific DNA binding; DNA-binding transcription factor activity; RNA polymerase II cis-regulatory region sequence-specific DNA binding; DNA-binding transcription factor activity, RNA polymerase II-specific; DNA-binding transcription repressor activity, RNA polymerase II-specific;
Cellular component	nucleus; intracellular membrane-bounded organelle;
Biological process	regulation of transcription, DNA-templated; transcription, DNA-templated; multicellular organism development; negative regulation of transcription by RNA polymerase II; cell fate determination; osteoblast development; segment specification; pattern specification process; motor neuron axon guidance; anterior/posterior pattern specification; dorsal/ventral pattern formation; rhombomere 2 development; rhombomere 3 development; rhombomere 3 morphogenesis; brain segmentation; middle ear morphogenesis; cell fate commitment; negative regulation of neuron differentiation; negative regulation of osteoblast differentiation; positive regulation of transcription by RNA polymerase II; embryonic viscerocranium morphogenesis; embryonic skeletal system morphogenesis; cellular response to retinoic acid; regulation of transcription by RNA polymerase II;
	Sources:Amigo / QuickGO
Orthologs
	3199
	15399
	ENSG00000105996
	ENSMUSG00000014704
	O43364
	P31245
	NM_006735
	NM_010451
	NP_006726
	NP_034581
	Wikidata
View/Edit Human	View/Edit Mouse

Homeobox protein Hox-A2 is a protein that in humans is encoded by the HOXA2 gene.^[5]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000105996 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000014704 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Scott MP (November 1992). "Vertebrate homeobox gene nomenclature". Cell. 71 (4): 551–3. doi:10.1016/0092-8674(92)90588-4. PMID 1358459. S2CID 13370372.

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000105996 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000014704 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid1358459-5] Scott MP (November 1992). "Vertebrate homeobox gene nomenclature". Cell. 71 (4): 551–3. doi:10.1016/0092-8674(92)90588-4. PMID 1358459. S2CID 13370372.

HOXA2 information

and 10 Related for: HOXA2 information

HOXA2

Hox gene

List of human transcription factors

Homeobox

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CHD8

Rhombomere

List of OMIM disorder codes

Homeobox A1

HOXB2