Guanylate cyclase activator 2B information

GUCA2B
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	1UYA, 1UYB
Identifiers
Aliases	GUCA2B, GCAP-II, UGN, guanylate cyclase activator 2B
External IDs	OMIM: 601271; MGI: 1270851; HomoloGene: 5150; GeneCards: GUCA2B; OMA:GUCA2B - orthologs
Gene location (Human)
Chr.	Chromosome 1 (human)
End	42,155,820 bp
Gene location (Mouse)
Chr.	Chromosome 4 (mouse)
End	119,516,151 bp
RNA expression pattern
	Top expressed in
	mucosa of ileum; ; mucosa of transverse colon; ; mucosa of sigmoid colon; ; jejunal mucosa; ; duodenum; ; rectum; ; testicle; ; right lobe of liver; ; body of stomach; ; epithelium of colon;
	Top expressed in
	right kidney; ; crypt of lieberkuhn of small intestine; ; duodenum; ; ileum; ; human kidney; ; jejunum; ; proximal tubule; ; epithelium of small intestine; ; intestinal villus; ; migratory enteric neural crest cell;
	More reference expression data
	n/a
Gene ontology
Molecular function	guanylate cyclase activator activity; calcium sensitive guanylate cyclase activator activity;
Cellular component	photoreceptor outer segment; extracellular exosome; extracellular region;
Biological process	cGMP biosynthetic process; excretion; body fluid secretion; negative regulation of blood pressure; positive regulation of guanylate cyclase activity; digestion; cGMP-mediated signaling;
	Sources:Amigo / QuickGO
Orthologs
	2981
	14916
	ENSG00000044012
	ENSMUSG00000032978
	Q16661
	O09051
	NM_007102
	NM_008191
	NP_009033
	NP_032217
	Wikidata
View/Edit Human	View/Edit Mouse

Guanylate cyclase activator 2B is a protein that in humans is encoded by the GUCA2B gene. ^[5]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000044012 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000032978 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Entrez Gene: Guanylate cyclase activator 2B". Retrieved 2017-07-04.

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